Itraconazole is not available over the counter. It is available by prescription only from a licensed provider.

In need of a prescription? Book a same-day appointment with a Sesame provider so you can start feeling better fast. Sesame providers are available 24/7 in all 50 states.

Side effects from itraconazole are generally mild, and most people tolerate it well.

Common side effects of itraconazole include:

• Nausea
• Diarrhea
• Abdominal pain
• Vomiting
• Constipation
• Gingivitis (swelling of the gums)
• Gas
• Indigestion
• Increased appetite

Itraconazole can also cause more serious side effects. Itraconazole may cause high blood pressure and even heart failure. If you experience any of the following symptoms, get medical help right away:

• Chest pain
• Shortness of breath
• Fatigue
• Swelling of the legs or abdomen
• Sudden weight gain
• Wheezing
• Chest congestion

Itraconazole may also cause peripheral neuropathy. If you experience numbness or tingling in the hands or feet, call your provider. It usually resolves once the medication is discontinued.

Itraconazole is also associated with liver damage, which can be mild to severe. Those with preexisting liver disease or those who are taking other medications that could damage the liver are at an increased risk.

Get medical care if you experience any of the following signs of liver damage:

• Yellowing of the skin or eyes
• Swelling in the legs or abdomen
• Itchy skin
• Excessive bruising
• Dark urine
• Pale-colored stool
• Confusion

Hypersensitivity or allergic reactions are also possible with itraconazole. These reactions can occur at the beginning or the end of treatment. Symptoms include severe rashes, hives, trouble breathing, and swelling of the face, lips, or tongue. Go to the closest emergency room if you experience any severe symptoms or signs of an allergic reaction.

Itraconazole is often used to treat severe fungal infections or hard-to-treat infections. The dosage will vary depending on the type of infection being treated. Your provider will determine the proper dosage and length of treatment based on your symptoms.

For oral thrush, the typical dosage is 200 mg of itraconazole oral solution once a day for 7 to 28 days. For toenail fungus, the typical dose is 200 mg once daily for 12 weeks.

Yes, Sporanox can treat yeast infections, although it is usually not the first choice. Itraconazole may be used if other medications do not work or if the patient cannot tolerate them.

Itraconazole is effective against yeast infections of the mouth, esophagus, and vagina.

Fluconazole is often the first choice for treating yeast infections as a single dose is often effective.

Itraconazole interacts with many different medications. Some medications may require dosage adjustments, while others may require you to avoid itraconazole entirely. It is important to tell your healthcare provider about all prescription and over-the-counter medications, vitamins, and supplements you take. They will ensure that itraconazole is safe for you to take.

Speak with your provider if you take any of the following medications:

• Antacids
• Benzodiazepines
• Blood thinners
• Cholesterol medications
• Heart failure medications
• Heart rhythm medications
• High blood pressure medications
• Immunosuppressants
• Migraine medications
• Opioid pain medications

This is not a complete list of drug interactions with itraconazole.

Itraconazole may not be safe for everyone. You should avoid taking itraconazole if you:

• Have heart failure
• Have Liver disease
• Are pregnant
• Are breastfeeding

Itraconazole is usually dosed one to three times a day, depending on the type of infection being treated. Itraconazole comes as capsules and an oral solution. Take the capsules with food to improve absorption. They should be swallowed whole, not chewed or crushed. The 100 mg capsule requires an acidic stomach environment, so antacids should be avoided within two hours of taking itraconazole. Your provider may recommend taking itraconazole with a non-diet soda to improve absorption.

Itraconazole solution should be taken on an empty stomach. If you are taking itraconazole for oral or esophageal thrush, the solution should be vigorously swished in the mouth before swallowing.

You can get an itraconazole prescription online after an appointment with a Sesame provider. You will meet with your provider over a live video visit to determine if itraconazole is appropriate for you. If approved, your prescription can be sent to an online pharmacy for delivery or to a local pharmacy for pickup.

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