Tirzepatide online prescriptions

Book a visit with a provider on Sesame to see if tirzepatide or another GLP-1 medication is right for you.

Tirzepatide prescriptions available, if appropriate
Prescription pickup available at a pharmacy near you
Insurance coordination for medication coverage
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Product Overview

Tirzepatide

  • What is tirzepatide (Mounjaro, Zepbound)?
    Tirzepatide is an active ingredient in several different brands of prescription drugs that have been FDA-approved for weight loss or type 2 diabetes.

    Zepbound, a brand-name drug, is FDA-approved to treat weight loss in patients with obesity and overweight. Zepbound is prescribed in conjunction with other treatment measures such as exercise and dietary changes to help patients lose weight and prevent serious weight-related health issues.

    Mounjaro is a brand-name drug FDA-approved to treat type 2 diabetes. While it uses the same active ingredient as Zepbound, the FDA has not approved it for weight loss.

    Talk to a healthcare provider to see if tirzepatide is right for you. Note that because Mounjaro is not FDA-approved for weight loss it is unlikely that insurance will cover the drug for weight loss. Zepbound is the only tirzepatide injection medication approved for weight loss.

  • What are the most common side effects of tirzepatide?
    Tirzepatide has been shown to cause adverse side effects in some patients. If these reactions become severe or do not go away after a day or two, seek medical attention right away.


The most common side effects of tirzepatide use include:

  • Upset stomach
  • Gas
  • Constipation
  • Diarrhea
  • Loss of appetite
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Frequently asked questions about tirzepatide

Medically reviewed by:
Dr. Allison Edwards, MD

Tirzepatide is the active ingredient in the brand name medications Zepbound and Mounjaro.

Mounjaro is FDA-approved to treat type 2 diabetes.

Zepbound is FDA-approved for weight loss in patients with obesity or who are overweight with other comorbidities such as high blood pressure, PCOS or obstructive sleep apnea.

Mounjaro is not FDA-approved to promote weight loss. The use of Mounjaro to help with weight loss is strictly off-label, meaning that weight loss is not the primary use of either of these drugs.

Tirzepatide is the active ingredient in the brand name medications Zepbound and Mounjaro.

Mounjaro is FDA-approved to treat type 2 diabetes.

Zepbound is FDA-approved for weight loss in patients with obesity or who are overweight with other comorbidities such as high blood pressure, PCOS or obstructive sleep apnea.

Mounjaro is not FDA-approved to promote weight loss. The use of Mounjaro to help with weight loss is strictly off-label, meaning that weight loss is not the primary use of this drug.

Tirzepatide works through its dual action on the GIP and GLP-1 receptors.

These actions include:

  • Stimulating the release of insulin from the pancreas in response to high blood sugar levels (glucose-dependent insulinotropic effect).
  • Reducing the release of glucagon, which helps lower blood sugar levels.
  • Slowing down stomach emptying, which can help control appetite and reduce food intake.
  • Promoting a sense of fullness after meals.

Overall, tirzepatide helps lower blood sugar levels and supports weight management in individuals with type 2 diabetes by regulating appetite and improving insulin response.

The use of tirzepatide may lead to side effects, although not everyone will experience them.

Common side effects may include:

  • Upset stomach
  • Gas
  • Constipation
  • Diarrhea
  • Loss of appetite

More severe side effects are less common but may include:

  • Severe stomach pain
  • Vomiting
  • Hives
  • Difficulty breathing
  • Changes in heartbeat
  • Fever
  • Skin rash
  • Heartburn
  • Swelling

If you experience any unusual or severe side effects or have concerns about them, consult your healthcare provider.

Before starting treatment with tirzepatide, inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with tirzepatide.

Specifically, tell your healthcare provider if you have a history of:

  • Pancreatitis or gallbladder disease
  • Thyroid problems
  • Kidney problems
  • Stomach or intestinal problems

Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding, as the use of tirzepatide during pregnancy and lactation should be discussed to assess potential risks and benefits.

The dosing of tirzepatide may vary depending on your individual needs and your healthcare provider's guidance. Typically, tirzepatide is administered as a subcutaneous injection once a week.

Your healthcare provider will determine the initial dose and any dose adjustments based on your response and the goal of achieving optimal blood sugar control and weight management.

Do not discontinue or change your tirzepatide dosage without consulting your health care provider.

Take the medication exactly as prescribed, and inform your doctor if you experience any side effects or have concerns while taking the medication.

Tirzepatide should be stored as directed by your health care provider or according to the medication's packaging instructions. Follow the recommended storage conditions, keeping the medication in the refrigerator or at room temperature.

Tirzepatide is currently only available with a prescription. A licensed healthcare provider must authorize the use of this medication.

Looking for a prescription? Providers on Sesame can assess your eligibility and prescribe tirzepatide if it's appropriate for your medical condition and needs. You can arrange for same-day pickup at your pharmacy, depending on the medication. Book an online consultation with a licensed provider on Sesame today to determine whether tirzepatide might be right for you. Providers on Sesame are unable to prescribe controlled substances.

Note that all prescriptions are at the discretion of your health care provider. Sesame cannot guarantee that you will be provided a prescription after a video or in-person appointment.

Providers on Sesame can help you get a prescription for tirzepatide, which you can pick up at a pharmacy near you, often on the same day. Don't wait to get your prescription filled—talk to a provider on Sesame today and streamline the process for convenient pickup from a pharmacy of your choice.

Please remember that the decision to prescribe tirzepatide is at the discretion of your health care provider.

Tirzepatide is only available under the brand names Zepbound and Mounjaro.

Sesame’s online weight loss program is a subscription that renews every 3 months and includes a video consultation with a weight loss provider, a prescription for semaglutide, liraglutide, tirzepatide, or other weight loss medication if deemed clinically appropriate, assistance with pre-authorization for medication coverage, and 90 days of unlimited messaging with your provider.

Sesame does not accept insurance in order to keep prices low and transparent, which means that the cost of the weight program will not be covered by insurance. It's important to note that the cost of medication is not included in this program, and Sesame does not guarantee medication pricing or insurance coverage for medication.

In addition, most insurance companies will not cover the off-label use of prescription drugs. __That means you will likely not be able to get insurance coverage if you are prescribed:

  • Ozempic
  • Rybelsus
  • Mounjaro
  • Victoza

If you are uninsured, please be aware that GLP-1 medications like Wegovy can be expensive, typically ranging between $950 to $1,600 per month. If you are insured, your provider can assist with insurance pre-authorization paperwork to cover the cost of your medication.

Your provider may order a metabolic panel if you do not have recent metabolic testing data available. If this is the case, the price of your lab test is not included in the program cost.

Certain GLP-1 therapies such as semaglutide (the active ingredient in Ozempic and Wegovy), liraglutide (the active ingredient in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound) may increase the likelihood of developing thyroid gland tumors, including medullary thyroid carcinoma (MTC), a type of thyroid cancer. This conclusion is based on studies where laboratory animals given semaglutide, liraglutide and tirzepatide developed tumors. However, it is not yet confirmed whether semaglutide, liraglutide and tirzepatide pose the same risk to humans.

It’s important to inform your doctor if you or any family member has ever had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), a condition leading to tumors in multiple glands. If this is the case, your doctor will likely advise against taking GLP-1 medications such as semaglutide, tirzepatide or liraglutide.

If you are prescribed a GLP-1 medication such as Ozempic, Wegovy, Mounjaro or Saxenda and exhibit any of the following symptoms, you should contact your provider immediately:

  • A lump or swelling in the neck
  • Hoarseness
  • Difficulty swallowing
  • Shortness of breath

Before taking GLP-1 medications, you should also discuss the following with your provider:

  • Allergies: Inform your doctor and pharmacist of any allergies you have to semaglutide (including under brand names Ozempic, Rybelsus, Wegovy) or similar medications such as tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy), and lixisenatide (Adlyxin, or in Soliqua).
  • Personal and family medical history: Be sure to disclose if you have a history of conditions like pancreatitis, diabetic retinopathy, gallbladder disease, or kidney disease. Inform your doctor about recent episodes of diarrhea, nausea, or vomiting, or any inability to consume liquids, which could lead to dehydration.
  • Current Medications and Supplements: Provide a comprehensive list of all medicines and supplements you are currently taking, including prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products. This is crucial as GLP-1 medications can alter how your body absorbs oral medications.
  • Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon.
  • Surgical procedures: In the event of surgery, including dental procedures, inform the medical or dental professional that you are on GLP-1 medication.

It's essential to thoroughly discuss these risks with your healthcare provider and consider your personal and family medical history when deciding whether to use these medications. Your doctor can provide guidance on the best course of action based on your specific health situation.

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