Tirzepatide has been shown to cause adverse side effects in some patients. If these reactions become severe or do not go away after a day or two, seek medical attention right away.
Mild side effects reported from tirzepatide use include:
- Upset stomach
- Loss of appetite
More serious side effects include:
- Severe stomach pain
- Difficulty breathing
- Changes in heartbeat
- Skin rash
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a possibly serious adverse reaction to this medication and require treatment right away.
In both male and female rats, tirzepatide has been linked to the development of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC). It is unknown whether or not tirzepatide causes these tumors in humans. However, tirzepatide is contraindicated in patients with a personal or family history of MTC. It is also contraindicated in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Patients with these conditions may receive counseling from their health care provider about the risks associated with tirzepatide use.
As with all medication, inform your doctor of any medical conditions you are currently managing. Tell them about any and all medication, prescription drugs, and supplements you are taking before starting treatment with tirzepatide. Tirzepatide can interact with substances in the body, causing potentially serious adverse reactions.
Tell your doctor if you have had pancreas or kidney disease, as well as any stomach/ digestive problems you have.
In addition, let your doctor know if you are planning to become pregnant, are pregnant, or are currently breastfeeding before starting treatment with this medication. Call your provider if you become pregnant while you are taking tirzepatide.