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Product Overview

Fluoxetine (generic Prozac)

  • What is fluoxetine?
    Fluoxetine (generic Prozac) is a prescription drug used to treat major depressive disorder, obsessive-compulsive disorder (OCD), PTSD, bulimia, and panic disorder.

  • What are common side effects of fluoxetine?
    While adverse reactions to fluoxetine are rare, some patients who take the drug experience mild side effects, including abnormal dreams, abnormal ejaculation, anorexia, anxiety, weakness or lack of energy, diarrhea, dry mouth, indigestion, flu syndrome, impotence, insomnia, libido decreased, nausea, nervousness, soreness of the throat or sinus, rash, drowsiness, sweating, tremor, and low blood pressure.

    Rare, more serious adverse events have also been known to occur. If you are concerned that fluoxetine is causing any number of these side effects, please contact your doctor.

    In rare cases, this and other SSRIs have been shown in rare cases to increase suicidal thoughts and actions in patients under the age of 24. Patients should only begin escitalopram under the supervision of their provider. If you are feeling suicidal, call the National Suicide Prevention Lifeline at 800-273-8255, text them at 741741, or dial 911.

    This is not a complete list of side effects. For more information on adverse effects you may experience while taking fluoxetine, please visit the National Institutes of Health’s DailyMed webpage.

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Medically Reviewed By Dr. Allison Edwards, MD

Frequently asked questions about fluoxetine

Fluoxetine - sometimes sold under the brand name Prozac - is an antidepressant medication that is used to treat a range of psychological disorders such as depression, obsessive-compulsive disorder, bulimia, and more. It belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). SSRIs work by increasing the brain’s levels of serotonin, a naturally occurring chemical that helps regulate your mood.

The CDC estimates that nearly 19% of the U.S. population has experienced at least some symptoms of depression over the last year. Depression is caused by a wide range of factors - from chemical imbalances in the brain to traumatic events in your life - and is often characterized by a persistently depressed mood and a loss of interest in your daily activities and passions.

Antidepressants like fluoxetine are designed to help get your depression symptoms under control and help you feel like yourself again.

The Food and Drug Administration (FDA) has approved Fluoxetine to treat major depressive disorder (MDD), obsessive-compulsive disorder, bulimia, and panic disorder. It is also approved in combination therapy with olanzapine for the treatment of psychological conditions that have been resistant to other forms of treatment and for acute depressive episodes associated with bipolar disorder.

Fluoxetine is also sometimes used to relieve the symptoms of premenstrual dysphoric disorder (PMDD) and other conditions.

Fluoxetine is an antidepressant belonging to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). SSRIs work by blocking the reabsorption of serotonin in our brain cells. Serotonin is a hormone that your brain naturally produces and releases. It is usually associated with feelings of happiness and helps stabilize your mood. Sometimes, your brain reabsorbs the serotonin before it can take effect, depriving the brain of the chemicals that, simply put, make it feel good.

Fluoxetine blocks this reabsorption, which doctors call “reuptake,” to increase the amount of serotonin in circulation in your brain. It is believed that low levels of serotonin may cause depression and anxiety. The reduction of depression and anxiety has been shown to reduce episodes of binge eating helping to break the binge-purge cycles associated with Bulimia.

While there are some common side effects associated with fluoxetine, it is important to remember that your doctor prescribed this medication because they believe that its ability to balance your mental health outweighs any adverse conditions it may cause.

The most common side effects associated with Fluoxetine include abnormal dreams, abnormal ejaculation, anorexia, anxiety, weakness or lack of energy, diarrhea, dry mouth, indigestion, flu syndrome, impotence, insomnia, libido decreased, nausea, nervousness, soreness of the throat or sinus, rash, drowsiness, sweating, tremor, and low blood pressure.

Call your doctor right away if you experience any symptoms of an allergic reaction (such as rash, hives, itching, fever, swelling, or difficulty breathing or swallowing). Antidepressants such as Fluoxetine also increase the risk of a serious condition known as Serotonin Syndrome (symptoms may include agitation, confusion, rapid heart rate, high blood pressure, dilated pupils, twitching muscles, lack of coordination, muscle rigidity, heavy sweating, diarrhea, headache, shivering, and goosebumps).

Consult your healthcare provider or pharmacist for more information about the potential adverse effects of using Fluoxetine.

WARNING: In short-term studies of major depressive disorder (MDD) and other psychiatric disorders, antidepressants showed an increased risk of suicidal thinking and behavior in children, adolescents, and young adults compared to placebo. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior.

If you are experiencing suicidal thoughts, please call the National Suicide Prevention Lifeline at 800-273-8255 or dial 911 immediately.

This is not a complete list of fluoxetine side effects. For more infomation on adverse conditions you may experience while taking fluoxetine, please visit the National Institutes of Health’s DailyMed webpage.

It usually takes 4 to 6 weeks for noticeable improvements to your mood and behavior. You may experience improvements to some physical symptoms such as sleep, energy, and appetite. These improvements are generally a good indication that the medication is working.

The starting dose of Fluoxetine will vary depending on the nature and severity of your condition, as well as your age and preexisting conditions.

For patients with MDD and OCD, initial doses of fluoxetine usually start at 20 mg, taken once every morning. Patients with bulimia are usually prescribed a once-daily dose of 60 mg; those with panic disorder, a conde daily dose of 10 mg.

Use Fluoxetine only as directed by your doctor or pharmacist and ask them to clarify any part of the instructions that may be unclear. Continue to take Fluoxetine even if you begin to feel better. Consult if you wish to discontinue using Fluoxetine, as stopping abruptly may cause withdrawal symptoms and increases the risk of adverse effects.

Fluoxetine is currently only available via prescription. This means the use of this drug must be authorized by a licensed health care provider.

Providers on Sesame can write a prescription – or refill an existing one – during a virtual or in-person visit. Depending on the medication, you can arrange for same-day pickup at a pharmacy near you. Book an online consultation with a real, licensed provider on Sesame today to determine whether or not fluoxetine is right for you.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

Yes! Talk to a provider on Sesame and get your online doctor prescription or refill ordered right away for fast and convenient pickup from a pharmacy of your choice.

Note that all prescriptions are at the discretion of your clinician.

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