Most chest colds are caused by a viral infection, which will not respond to antibiotic therapy. Your doctor may recommend over-the-counter cough medicine to treat symptoms associated with a chest cold. An expectorant cough medicine (such as guaifenesin, otherwise known as Mucinex) helps break up mucus, making it easier to produce while coughing. This can improve your breathing and reduce wheezing. Additionally, your doctor may recommend that you pair cough medication with over-the-counter pain relievers such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin), to relieve discomfort and reduce fever-like symptoms caused by a chest cold.
If your doctor suspects the infection is being caused by bacteria - a rarer occurrence - you may be prescribed antibiotics as treatment.