Bupropion is quickly metabolized and is easily tolerable for most patients. Side effects are generally more mild and manageable than most antidepressant medications. There are some common side effects, however, that you may still encounter. These may include:
In some cases, bupropion may cause more severe side effects. If the effects above do not go away after a few days, or if adverse effects get worse, talk to your doctor right away. Severe side effects of bupropion may include:
Rapid or irregular heartbeat
WARNING: In short-term studies of major depressive disorder (MDD) and other psychiatric disorders, antidepressants showed an increased risk of suicidal thinking and behavior in children, adolescents, and young adults compared to placebo. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior.
If you are experiencing suicidal thoughts, please immediately call the National Suicide Prevention Lifeline at 800-273-8255 or 911.
This is not a complete list of side effects of bupropion. For more information on adverse effects you may experience, please visit the National Institutes of Health’s DailyMed page on bupropion.