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Get an ondansetron (Zofran) prescription online for nausea and vomiting

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Book care online with a Sesame provider and get an ondansetron prescription if it is right for you. Ondansetron (Zofran) is an anti-nausea medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking the action of serotonin, a natural chemical, in the brain and gut, which can trigger nausea and vomiting.

This medication can help you:

  • Block serotonin receptors in the brain and gut
  • Reduce nausea and vomiting
  • Maintain hydration and nutrition

Ondansetron may also be prescribed off-label for pregnancy-related nausea, particularly in the first trimester.

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About ondansetron (Zofran)

Learn more about ondansetron (Zofran), what it’s used to treat, and how to get ondansetron prescribed today.

How to get ondansetron (Zofran) prescribed online through Sesame

1
Choose a provider

Browse our website to read reviews online and pick a Sesame provider in your price range. Schedule a same-day appointment to discuss ondansetron (Zofran) treatment.

2
Meet with your provider

Meet directly with your provider from your smartphone or computer to discuss a treatment plan and whether ondansetron (Zofran) is an appropriate option for you.

3
Get your ondansetron prescription online

If your provider approves ondansetron (Zofran), they will send the prescription directly to your local pharmacy for same-day pickup if available.

Ondansetron (Zofran) possible side effects and safety considerations

Learn about potential side effects and when to seek medical care

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Frequently asked questions

About ondansetron (Zofran)

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Medically reviewed by:Dr. Allison Edwards, MD

The cost of ondansetron (Zofran) will vary depending on whether you are getting brand-name ondansetron or generic ondansetron. Comparing prices at different pharmacies can help you find the cheapest option.

You can also use Sesame’s Rx savings card at the pharmacy checkout to save up to 80% on your medication.

No, ondansetron (Zofran) is only available by prescription from a licensed healthcare provider. Ondansetron can be ordered by a Sesame provider for same-day local pharmacy pickup. Schedule an appt today and get relief from nausea and vomiting.

All prescriptions are at the discretion of the provider.

Book an appointment for a video visit with a Sesame provider to determine if you are a good candidate for ondansetron. If they approve, a ondansetron (Zofran) prescription can be sent to your local pharmacy or to an online pharmacy for delivery to you.
Yes, ondansetron (Zofran) may make you sleepy. Fatigue and drowsiness are two of the most common side effects of ondansetron. In addition, fatigue often accompanies nausea and vomiting and can be a side effect of chemotherapy or surgery.

Ondansetron (Zofran) is not currently FDA-approved to treat nausea and vomiting during pregnancy, but is sometimes used off-label. It is recommended to try FDA-approved options first, but if those options are not effective, ondansetron may be considered for those with severe symptoms.

Ondansetron does cross the placenta, but results are conflicting on whether this can harm the fetus. It is important to discuss the risks of taking ondansetron during pregnancy with your provider.

Yes, while not FDA-approved, ondansetron (Zofran) can be used to ease nausea and vomiting from the stomach virus, with guidance from a healthcare provider. Severe vomiting can lead to dehydration and electrolyte imbalances. Treatment with ondansetron may allow the body to recover and to tolerate rehydration.
Ondansetron (Zofran) may start to ease nausea in about 30 minutes; however, it may take up to 2 hours before you feel better. Speak with your provider if ondansetron does not adequately control your symptoms.

Although your results may vary, ondansetron (Zofran) should last about 8 to 12 hours. It is important not to increase your dosage or take more than recommended by your provider.

If you feel ondansetron is wearing off quickly, reach out to your healthcare provider. They can recommend other options to get rid of nausea, including home remedies or other medications.

To reduce the risk of post-op nausea and vomiting, 16mg of ondansetron is given 1 hour before anesthesia.

Ondansetron ODT contains phenylalanine, so people with phenylketonuria (PKU) should avoid those tablets. Also, people who take apomorphine should avoid ondansetron as it can cause low blood pressure and heart rhythm changes.

Additionally, if ondansetron is used with other medications that can increase serotonin, it can cause serotonin syndrome. Symptoms of serotonin syndrome include anxiety, confusion, muscle stiffness, Increased heart rate, changes to blood pressure, and seizures.

If you took an ondansetron ODT tablet and then vomited, you do not need to take another dose. The medication should still work as intended. If you are unclear of what to do, reach out to your pharmacist or healthcare provider for specific guidance.