Medically reviewed by Jessica Swirble, PharmD
Last updated on March 27, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Amlodipine is a medication commonly prescribed to treat high blood pressure (hypertension) and certain types of chest pain (angina). It belongs to a class of drugs known as calcium channel blockers.
Amlodipine is primarily used to treat high blood pressure (hypertension) and angina (chest pain) caused by coronary artery disease. It may also be prescribed for other conditions related to blood vessel problems as determined by your healthcare provider.
Amlodipine works by blocking calcium channels in blood vessels and the heart muscle. This causes blood vessels to relax, which helps lower blood pressure and relieve chest pain.
Amlodipine is usually taken orally once daily, with or without food. It is important to take amlodipine consistently at the same time each day to maintain stable blood levels and maximize its effectiveness.
Consult your healthcare provider for specific instructions on how to take amlodipine properly.
The time it takes to experience improvements in your blood pressure or chest pain while taking amlodipine can vary. Some individuals may notice changes within a few days, while it may take several weeks for others to feel the full benefits. It's crucial to continue taking amlodipine as prescribed, even if you start feeling better, to ensure the best outcome.
While amlodipine is primarily used for hypertension and angina, healthcare providers may sometimes prescribe it off-label for other conditions, including:
Discuss any alternative uses of amlodipine with your healthcare provider.
Amlodipine is available in the following dosage forms:
Generic versions of amlodipine are available under various brand names.
Amlodipine is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this drug.
The use of amlodipine has been shown to cause side effects in some patients.
Common mild side effects of amlodipine use include:
More severe side effects include:
Seek medical attention immediately if you experience any severe symptoms while taking amlodipine. If you experience mild side effects that become severe or do not go away after a few days, speak to a healthcare provider right away.
Before starting treatment with amlodipine, tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with this drug.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using amlodipine to assess potential risks and benefits.
Try to take amlodipine around the same time every day.
Your healthcare provider may ask you to avoid grapefruit juice while taking amlodipine.
Follow your healthcare provider's instructions for monitoring your blood pressure and heart rate while taking amlodipine.
Your healthcare provider will provide specific instructions regarding the use of amlodipine with food, beverages, and other medications. It's essential to follow their guidance to ensure the effectiveness of the treatment and minimize the risk of side effects.
The symptoms of an amlodipine overdose include:
If you experience any of these symptoms, call the poison control helpline at 1-800-222-1222. If an individual has collapsed, is having seizures, or is unresponsive, call 9-1-1 immediately.
Amlodipine is available in various strengths, including:
The typical starting dose of amlodipine for high blood pressure (hypertension) can vary depending on factors such as your age, other medical conditions, and how you respond to the medication. It's essential to follow your healthcare provider's instructions regarding dosage and administration carefully.
For most adults with high blood pressure, the typical starting dose of amlodipine may be:
However, your healthcare provider may start with a lower dose, such as 2.5 mg, especially for older adults or those with certain medical conditions. The dose may then be gradually increased up to a maximum of 10 mg per day.
Amlodipine can be taken with or without food, but it's important to take it consistently at the same time each day.
Your healthcare provider will monitor your blood pressure and response to the medication and may adjust the dose as needed.
If you have any questions about your dosage or how to take amlodipine, contact your healthcare provider. If you want to talk to a provider right away, book an online doctor appointment on Sesame to discuss your concerns.
If you miss a dose, take it as soon as you remember it. If it's almost time for another dose of amlodipine, skip the missed dose and take your next dose as scheduled. Do not take a double dose of amlodipine.
Continue taking amlodipine as prescribed by your healthcare provider even if you start feeling better. Do not stop taking the medication without consulting your doctor, as abruptly discontinuing amlodipine can lead to an increase in blood pressure or other complications.
Store amlodipine as directed by your healthcare provider or pharmacist. Proper storage is essential to maintain the medication's effectiveness.
Amlodipine pills should be stored at room temperature, away from excessive heat, light, and moisture. Liquid amlodipine should be stored in the refrigerator.
Keep the medication out of the reach of children and ensure that the container is tightly closed.