Medically reviewed by Jessica Swirble, PharmD
Last updated on March 31, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed to relieve pain, inflammation, and swelling caused by various conditions such as arthritis, menstrual cramps, and injuries. It belongs to the class of medications known as NSAIDs.
Diclofenac is used to treat conditions such as:
It may also be prescribed for other inflammatory or painful conditions as determined by your healthcare provider.
Diclofenac works by reducing the production of certain chemicals in the body that cause pain, inflammation, and swelling. It inhibits an enzyme that is responsible for these symptoms.
Diclofenac is typically taken orally, usually with food, to prevent stomach upset and irritation. Extended-release diclofenac is also taken with food to help ensure a more consistent blood concentration of the drug.
It is important to follow the prescribed dosage and schedule. Do not take more than the recommended dose or use it for longer than prescribed.
Consult your healthcare provider for specific instructions on how to take diclofenac properly.
The time it takes to experience relief from pain or inflammation while taking diclofenac can vary depending on the condition being treated and individual response. Some people may notice improvement within a few days, while others may require several weeks of treatment. It's important to continue taking diclofenac as prescribed to achieve the best results.
While diclofenac is primarily used for pain and inflammation, healthcare providers may sometimes prescribe it off-label for other conditions, such as:
Discuss any alternative uses of diclofenac with your healthcare provider.
Diclofenac is available in the following dosage forms:
Generic versions of diclofenac are available under various brand names.
Diclofenac is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this drug.
The use of diclofenac has been shown to cause side effects in some patients.
Common mild side effects of diclofenac use include:
More severe side effects include:
Seek medical attention immediately if you experience any severe symptoms while taking diclofenac. If you experience mild side effects that become severe or do not go away after a few days, speak to a healthcare provider right away.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with diclofenac. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with this drug.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using diclofenac to assess potential risks and benefits.
You can follow your regular diet while taking diclofenac.
Avoid alcohol consumption while taking diclofenac, as it may increase the risk of stomach bleeding or other side effects.
Tell your doctor if you smoke before starting treatment with diclofenac.
Do not use diclofenac if you are allergic to it or other NSAIDs, or if you have a history of allergic reactions (e.g., asthma, hives) to these medications.
Your healthcare provider will provide specific instructions regarding the use of diclofenac with food, beverages, and other medications. It's essential to follow their guidance to ensure the effectiveness of the treatment and minimize the risk of side effects.
The symptoms of a diclofenac overdose include:
If you experience any of these symptoms, call the poison control helpline at 1-800-222-1222. If an individual has collapsed, is having seizures, or is unresponsive, call 9-1-1 immediately.
Diclofenac is available in the following forms:
Try to take diclofenac around the same time every day. Different diclofenac products release the drug into your body differently. The different forms of diclofenac are not interchangeable. Only use diclofenac as prescribed by your provider.
The recommended dosage of diclofenac may vary depending on the individual's condition and response to treatment. Your healthcare provider will determine the appropriate dosage and administration instructions. Take the medication exactly as prescribed, and inform your doctor if you begin to experience any side effects while taking the medication.
If you miss a dose, take it as soon as you remember it. If it's almost time for another dose of diclofenac, skip the missed dose and take your next dose as scheduled. Do not take or apply a double dose of diclofenac.
Continue taking diclofenac as prescribed even if you start feeling better, unless instructed otherwise by your healthcare provider. Abruptly stopping diclofenac can lead to rebound symptoms or complications.
Store diclofenac as directed by your healthcare provider or pharmacist. Proper storage is essential to maintain the medication's effectiveness. Diclofenac should be stored at room temperature, away from excessive heat, light, and moisture.
Keep the medication out of the reach of children and ensure that the container is tightly closed.