Medically reviewed by Jessica Swirble, PharmD
Last updated on 5/4/2024

Drug Information | Side Effects | Use & Dosage | Request a Prescription

Estradiol is available in the following forms:

• Oral tablets (0.5 mg, 1 mg, 2 mg)
  
• Transdermal patches (various dosages, typically ranging from 0.025 mg to 0.1 mg released daily)
  
• Topical gels and creams
  
• Vaginal creams, rings, and tablets
  
  

The typical starting dose of estradiol varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is important to follow your healthcare provider's instructions regarding dosage and administration.

For menopausal symptoms, the typical starting doses may be:

• Oral tablets: 0.5 mg to 1 mg daily.
  
• Transdermal patches: Applied once or twice a week depending on the brand and dosage.
  
  

For osteoporosis prevention or estrogen replacement, providers start patients on lower doses and adjust based on response.

Your healthcare provider will determine the most appropriate dose based on your medical history, current medications, and response to the medication.

Estradiol should be taken exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.

If you have any questions about your dosage or how to take this medication, contact your healthcare provider or pharmacist. If you want to talk to a provider right away, consider booking an online doctor appointment on Sesame to discuss your concerns.

If you miss a dose of estradiol, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Maintain a consistent dosing schedule to ensure the effectiveness of estradiol in managing your hormonal needs.

Continue taking estradiol as prescribed by your healthcare provider, even if you start feeling better. Do not stop the medication abruptly without consulting your provider, as it may lead to a recurrence of symptoms or other complications.

Complete the full course of treatment as directed to maintain the desired therapeutic benefits.

If you have any concerns or questions about your medication, discuss them with your healthcare provider for personalized guidance and recommendations.

Store estradiol according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from moisture, heat, and light. Ensure the container is tightly closed and out of reach of children.

Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.