Sesame Logo

Get an estradiol (generic Estrace) prescription online

Material Timer Icon

Same-day prescriptions

Material Local Pharmacy Icon

Local pharmacy pick-up

Material Credit Card Icon

Rx discount card available

Talk to a doctor today about an online prescription for estradiol (generic Estrace) to treat hot flashes, vaginal dryness, and other menopause symptoms. Any prescriptions will be sent for pickup at your local pharmacy.

Get a prescription today

Estradiol overview

Learn more about estradiol, what it's used to treat, and how you can get a estradiol prescription today.

Get the prescriptions you need at Sesame’s always-low prices.

Choose your own provider

Select a top-rated clinician who can offer customized support and symptom relief.

Same-day prescriptions

sent to your local pharmacy for both hormonal and non-hormonal menopause treatments.

Menopause care from anywhere

Get treatment at home or on-the-go with Sesame’s convenient mobile app.

Enter your email to get 20% off your first appointment.

Here's how Menopause subscription works.

1
Tell us about yourself

Fill out a brief questionnaire about your menopause symptoms to help us customize your treatment, then choose your provider.

2
See your provider as soon as today

During your video call, they’ll create a treatment plan based on your medical history & goals. Basic lab work is included, if necessary.

3
Begin treatment

Your provider will send any prescription(s) to your preferred pharmacy, and you’ll receive ongoing support via video care & messaging.

1
Tell us about yourself

Fill out a brief questionnaire about your menopause symptoms to help us customize your treatment, then choose your provider.

2
See your provider as soon as today

During your video call, they’ll create a treatment plan based on your medical history & goals. Basic lab work is included, if necessary.

3
Begin treatment

Your provider will send any prescription(s) to your preferred pharmacy, and you’ll receive ongoing support via video care & messaging.

How estradiol may affect you

Learn about potential side effects and when to seek medical care.

Patients love Sesame

FAQs

Frequently asked questions about estradiol

Avatar image
Medically reviewed by:Dr. Allison Edwards, MD

Yes! Providers on Sesame can prescribe estradiol online and send it to your local pharmacy if appropriate.

For a personalized menopause care plan and treatment, you can also access estradiol prescriptions through Sesame’s menopause subscription if appropriate. The subscription includes video visits with a provider of your choice and lab work to assess your hormonal health. It also includes access to prescriptions to treat menopause symptoms like hot flashes, vaginal dryness, insomnia, mood swings and more.

Note that all prescriptions are at the discretion of your doctor.

Estradiol is currently only available via prescription. This means the use of this drug must be authorized by a licensed health care provider.

Providers on Sesame can write a prescription – or refill an existing one – during a virtual or in-person visit. Depending on the medication, you can arrange for same-day pickup at a pharmacy near you. Book an online consultation with a real, licensed provider on Sesame today to determine whether or not estradiol is right for you.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

Yes, an online doctor or provider on Sesame can write or refill a prescription during your telehealth visit. Clinicians on Sesame can prescribe medications to help treat infections, UTIs, anxiety, depression, allergies, high blood pressure, erectile dysfunction, and more.

If medication is prescribed during your online visit, your provider will send your prescription to your preferred pharmacy for same-day pickup.

Note that providers on Sesame cannot prescribe controlled substances.

Yes, online prescription refill appointments on Sesame are available 24/7 in all 50 states. You can book these visits whenever you need to talk to a health care provider about a new prescription or prescription refill.
It depends! Providers on Sesame can typically assist with refilling 1-2 existing prescriptions during a prescription refill appointment. If you require additional medication, your provider may require a longer or additional visit so that there is time to adequately review and assess your medication needs.

All visits on Sesame are cash-pay only; we do not accept insurance in order to keep prices low and transparent. However, if you do have health insurance and are prescribed medication during your appointment, your prescription may be covered depending on your plan.

When you pick up your medication at your pharmacy, the pharmacist can check your coverage using the insurance they have on file or the information you provide.

To see if your medication is covered and what your copay will be, you can also check your insurance plan’s drug formulary or contact your insurance provider directly.

You don’t usually need a previous prescription to get a prescription online. A licensed provider can write a new one after reviewing your health history and symptoms during a telehealth visit. Ultimately, the decision to prescribe medication is up to your provider and whether or not they think the medication is right for you.

However, if you are refilling an existing medication, your Sesame provider may ask you to see a picture of an old pill bottle or see prior prescription records to confirm your medication dosage needs. Your Sesame provider may also be able to look up your past prescriptions from other doctors through a national pharmacy system.

Join our mailing list for exclusive promos, curated health content & more.
FacebookXLinkedIn
© 2025 Sesame, Inc. All rights reserved.