Medically reviewed by Jessica Swirble, PharmD
Last updated on April 17, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Fluconazole is an antifungal medication used to treat various fungal infections, including yeast infections (candidiasis), oral thrush, vaginal yeast infections, and certain types of meningitis caused by fungi. It belongs to the azole class of antifungals.
Fluconazole is used to treat conditions such as:
It may also be prescribed for other fungal infections as determined by your healthcare provider.
Fluconazole works by interfering with the synthesis of fungal cell membranes, leading to the disruption of fungal growth and reproduction. It effectively targets fungal cells while sparing human cells, making it an effective treatment for various fungal infections.
Fluconazole is usually taken orally with or without food, as directed by your healthcare provider. The dosage and duration of treatment depend on the type and severity of the fungal infection.
Follow the prescribed dosage and schedule strictly. Do not stop taking fluconazole suddenly without consulting your healthcare provider, as it may lead to the recurrence of the infection.
The time it takes to see improvements in fungal infections can vary depending on the type of infection and individual response. Some infections may improve within a few days of starting fluconazole, while others may require longer treatment durations.
Continue taking fluconazole as prescribed even if your symptoms improve. Complete the full course of treatment to ensure the infection is fully eradicated.
While fluconazole is primarily used for fungal infections, healthcare providers may sometimes prescribe it off-label for other conditions, such as:
Discuss any alternative uses of fluconazole with your healthcare provider.
Fluconazole is available in the following dosage forms:
Generic versions of fluconazole are available under various brand names.
Fluconazole is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this medication.
The use of fluconazole can lead to various side effects in some individuals.
Common mild side effects of fluconazole use include:
More severe side effects of fluconazole use can include:
If you experience any severe or concerning side effects while taking fluconazole, contact your healthcare provider promptly.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with fluconazole. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with fluconazole.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using fluconazole to assess potential risks and benefits.
Take fluconazole exactly as prescribed by your healthcare provider. Do not skip doses or stop the medication prematurely, even if you start feeling better.
Fluconazole can be taken with or without food. Swallow the tablet whole with a full glass of water.
Avoid alcohol while taking fluconazole, as it may increase the risk of side effects and reduce the effectiveness of the medication.
If you are using fluconazole for a vaginal yeast infection, abstain from sexual activity until the infection is fully treated to prevent transmission.
Store fluconazole at room temperature, away from moisture and heat. Keep it out of reach of children.
In case of a fluconazole overdose, seek medical attention immediately. Symptoms of overdose may include severe nausea, vomiting, diarrhea, and dizziness. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.
Fluconazole is available in the following forms:
Typical starting dose for vaginal yeast infections:
Typical starting dose for candidiasis (thrush):
Typical starting dose for cryptococcal meningitis:
Fluconazole is available in oral tablet and suspension forms. It should be taken orally with or without food, as directed by your healthcare provider. Follow the prescribed dosage and schedule strictly for optimal effectiveness.
The dosage of fluconazole recommended for you will depend on various factors such as the type and severity of the infection, your medical history, and your response to the medication. Take fluconazole exactly as prescribed by your provider.
If you have any questions about your dosage or how to take this medication, contact your healthcare provider or pharmacist. If you want to talk to a provider right away, consider booking an online doctor appointment on Sesame to discuss your concerns.
If you miss a dose of fluconazole, take it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Continue taking fluconazole as prescribed by your healthcare provider, even if you start feeling better. It is important to complete the full course of treatment to ensure the infection is fully eradicated. Do not stop taking fluconazole without consulting your provider.
Store fluconazole according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from moisture, heat, and light. Ensure the container is tightly closed and out of reach of children.