Medically reviewed by Jessica Swirble, PharmD
Last updated on March 31, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Lisinopril is a medication prescribed to manage high blood pressure (hypertension), heart failure, and improve survival following a heart attack. It belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors.
Lisinopril is used to treat the following conditions:
It may also be prescribed for other cardiovascular conditions as determined by your healthcare provider.
Lisinopril works by relaxing blood vessels, which helps lower blood pressure and improves blood flow, reducing the workload on the heart. This can help manage hypertension and heart failure.
Lisinopril also decreases the amount of sodium and water in the body, which contributes to lower blood pressure.
Lisinopril is typically taken orally once a day, with or without food. Your healthcare provider will determine the appropriate dosage based on your medical condition and response to treatment.
Consult your healthcare provider for specific instructions on how to take lisinopril properly.
The time it takes to see improvements in your condition while taking lisinopril can vary. It may take several weeks to experience the full benefits of the medication. Continue taking lisinopril as prescribed even if you feel well, as sudden discontinuation can lead to your condition getting worse.
While lisinopril is primarily used to lower blood pressure, it may also be prescribed for other purposes, including:
Discuss any alternative uses of lisinopril with your healthcare provider.
Lisinopril is available in various dosage forms, including:
Generic versions of lisinopril are available under various brand names.
Lisinopril is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this drug.
The use of lisinopril has been shown to cause side effects in some patients.
Common mild side effects of lisinopril use include:
More severe side effects include:
Seek medical attention immediately if you experience any severe symptoms while taking lisinopril. If you experience mild side effects that become severe or do not go away after a few days, speak to a healthcare provider right away.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with lisinopril. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with this drug.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using lisinopril to assess potential risks and benefits.
You can follow your regular diet while taking lisinopril. Talk to your healthcare provider about the use of this drug with food, beverages, alcohol, and tobacco.
Your doctor may order you to eat a low-sodium diet while you are taking lisinopril. Tell your provider if you use salt substitutes containing potassium.
Your healthcare provider will provide specific instructions regarding the use of lisinopril with food, beverages, and other medications. It's essential to follow their guidance to ensure the effectiveness of the treatment and minimize the risk of side effects.
The symptoms of a lisinopril overdose include:
If you experience any of these symptoms, call the poison control helpline at 1-800-222-1222. If an individual has collapsed, is having seizures, or is unresponsive, call 9-1-1 immediately.
Lisinopril is available in various strengths, including:
The typical starting dose of lisinopril for hypertension (high blood pressure) can vary depending on factors such as the severity of hypertension, other medical conditions, and individual response to the medication. It is crucial to follow your healthcare provider's instructions regarding dosage and administration carefully.
For most patients with hypertension, the typical starting dose of lisinopril may be:
However, your healthcare provider may adjust the dose based on your blood pressure response. Some patients may start with a lower dose of 2.5 mg or 5 mg, especially if they are also taking diuretics or have certain medical conditions.
For heart failure or post-heart attack treatment, the typical starting dose may be lower and then gradually increased under medical supervision.
Your healthcare provider will monitor your blood pressure, kidney function, and overall health to determine the most appropriate starting dose and any necessary adjustments.
Lisinopril should be taken exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or make changes to your medication regimen without consulting your provider.
If you have any questions about your dosage, contact your healthcare provider. If you want to talk to a provider right away, book an online doctor appointment on Sesame to discuss your concerns.
If you miss a dose, take it as soon as you remember it. If it's almost time for another dose of lisinopril, skip the missed dose and take your next dose as scheduled. Do not take or apply a double dose of lisinopril.
Even if you start feeling better, do not stop taking lisinopril without consulting your healthcare provider. Abruptly stopping use can lead to a sudden increase in blood pressure or a worsening of your condition. Your doctor may need to gradually reduce your dose to avoid these effects.
Attend follow-up appointments as recommended by your healthcare provider for blood pressure monitoring and adjustments to your lisinopril dosage if needed.
Store lisinopril as directed by your healthcare provider or pharmacist. Proper storage is essential to maintain the medication's effectiveness. Lisinopril should be stored at room temperature, away from excessive heat, light, and moisture.
Keep the medication out of the reach of children and ensure that the container is tightly closed.