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Ondansetron

Common Brand Names: Zofran

Proper Use & Dosage Information

Medically reviewed by Jessica Swirble, PharmD
Last updated on 5/24/2024

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What is the typical starting dose for ondansetron?

Ondansetron is available in the following forms:

  • Oral tablets
  • Orally disintegrating tablets (ODTs)
  • Oral solution

The typical starting dose of ondansetron varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.

For prevention of nausea and vomiting caused by chemotherapy:

  • Adults: Typically, 8-24 mg is given 30 minutes before chemotherapy, followed by another dose a few hours later.
  • Children: Dosage is based on body weight and must be determined by your doctor.

For nausea and vomiting after surgery:

  • Adults: 16 mg given 1 hour before anesthesia.
  • Children: Dosage is based on body weight and must be determined by your doctor.

The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history and your response to the medication.

Ondansetron should be taken as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.

If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.

What should I do if I miss a dose of ondansetron?

If you miss a dose of ondansetron, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not double the dose to make up for a missed one.

Take ondansetron around the same time every day to maintain an even level of medication in your body.

What should I do if I'm feeling better while taking ondansetron?

Continue taking ondansetron as prescribed by your healthcare provider, even if you start feeling better. It's important to keep taking the medication as directed to manage your condition effectively.

If you have any concerns or questions about your medication, discuss them with your healthcare provider for medical advice and recommendations.

How should I store ondansetron?

Store ondansetron according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from light and moisture. Ensure the container is tightly closed and out of reach of children.

Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.