Medically reviewed by Jessica Swirble, PharmD
Last updated on April 17, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Pantoprazole is a medication used to treat damage to the esophagus from gastroesophageal reflux disease (GERD). It belongs to a class of medications known as proton pump inhibitors, which work by decreasing the production of stomach acid, which causes damage from GERD.
Pantoprazole is used to treat conditions caused by excessive production of stomach acid. This includes:
Damage from GERD: Stomach acid from GERD can damage the esophagus, leading to scarring. Pantoprazole decreases the production of stomach acid, allowing the damage to heal.
Zollinger-Ellison syndrome: A rare disorder in which the stomach produces too much acid, leading to ulcers and esophageal damage.
Pantoprazole belongs to a class of medications known as proton pump inhibitors. These drugs work by decreasing the production of stomach acid.
Pantoprazole is available in the following forms:
The dosage and length of treatment depend on the condition being treated, its severity, and how you tolerate the medication.
Follow your healthcare provider's instructions regarding dosage and schedule. Do not exceed the prescribed dose or duration of treatment without consulting your provider.
Pantoprazole is available in various forms:
The oral granules can be sprinkled on 1 teaspoon of cool applesauce and swallowed within 10 minutes. Do not crush or chew the granules. The granules can also be mixed with 1 teaspoon of apple juice and then swallowed. The container should be rinsed with additional apple juice and then swallowed. Do not mix with other liquids or foods, including water.
The dosage and length of treatment depend on the condition being treated, its severity, and how you tolerate the medication.
Follow your healthcare provider's instructions regarding dosage and schedule. Do not exceed the prescribed dose or duration of treatment without consulting your provider.
The effectiveness of pantoprazole and the time it takes to notice improvement can vary among individuals. For conditions like gastroesophageal reflux disease (GERD), you may start to feel relief from symptoms within a few days, but it can take up to several weeks for full therapeutic effects.
Continue taking pantoprazole as prescribed even if you start feeling better. Do not abruptly stop the medication, as it may lead to a return of symptoms or increased acid production.
While pantoprazole is primarily used for treating conditions involving excessive stomach acid, such as GERD and Zollinger-Ellison syndrome, healthcare providers may sometimes prescribe it off-label for other gastrointestinal conditions.
Discuss any alternative uses of pantoprazole with your healthcare provider.
Pantoprazole is available in the following dosage forms:
Generic versions of pantoprazole are available.
Pantoprazole is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this medication.
The use of pantoprazole can lead to various side effects in some individuals.
Common mild side effects of pantoprazole use include:
More severe side effects of pantoprazole use can include:
If you experience any severe or concerning side effects while taking pantoprazole, contact your healthcare provider right away.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with pantoprazole. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with pantoprazole.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using pantoprazole to assess potential risks and benefits.
Take pantoprazole exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment.
Pantoprazole can impair your ability to absorb certain vitamins and minerals. Be aware of any symptoms of deficiencies, such as muscle cramps or irregular heartbeat, which could suggest low magnesium levels.
Take pantoprazole at the same time every day, usually in the morning before eating. Pantoprazole should be taken on an empty stomach about 30 to 60 minutes before meals.
In case of a pantoprazole overdose, seek medical attention immediately. Symptoms of overdose may include confusion, dizziness, blurred vision, dry mouth, flushing, headache, nausea, and sweating. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.
Pantoprazole is available in the following forms:
The typical starting dose of pantoprazole varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.
For short-term treatment of erosive esophagitis:
For the maintenance of erosive esophagitis healing:
For Zollinger-Ellison syndrome:
The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history, current medications, and response to the medication.
Pantoprazole should be taken exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.
If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.
If you miss a dose of pantoprazole, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
Take pantoprazole around the same time every day to ensure effectiveness.
Continue taking pantoprazole as prescribed by your healthcare provider, even if you start feeling better. Do not stop the medication abruptly without consulting your provider, as it may lead to a return of symptoms.
If you have any concerns or questions about your medication, discuss them with your healthcare provider for medical advice and recommendations.
Store pantoprazole according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from light and moisture. Ensure the container is tightly closed and out of reach of children.
Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.