Medically reviewed by Jessica Swirble, PharmD
Last updated on April 18, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Quetiapine is an atypical antipsychotic drug that is used to treat patients with schizophrenia as well as mania and depression related to bipolar disorder. Extended-release quetiapine is prescribed to treat depression.
Quetiapine is prescribed to treat symptoms of schizophrenia. It is also prescribed to treat mania and depression symptoms associated with bipolar disorder. When prescribed as an extended-release tablet, quetiapine can be used to treat depression in adults.
Quetiapine is classified as an atypical antipsychotic. It works by increasing levels of serotonin and dopamine in the brain. Serotonin and dopamine are neurotransmitters that help regulate mood. Balancing these chemicals’ levels in the brain can work to reduce symptoms of schizophrenia, bipolar disorder, and major depressive disorder (depression).
Quetiapine is prescribed in conjunction with other medications and psychotherapy (“talk therapy”).
Quetiapine is available as an oral tablet and an extended-release tablet.
Follow your healthcare provider's instructions regarding dosage and schedule. Do not exceed the prescribed dose or frequency of use without consulting your provider.
Quetiapine is used to manage schizophrenia, bipolar disorder, and major depressive disorder (as an adjunct therapy). The effects can be noticeable within a few weeks, but it may take up to four to twelve weeks for the full therapeutic effect to occur.
Continue using quetiapine as prescribed, even if you start feeling better. Regular use according to your prescription is crucial for the management of your condition.
While quetiapine is primarily used for treating schizophrenia, bipolar disorder, and major depressive disorder, healthcare providers may prescribe it off-label for other conditions such as anxiety or insomnia.
Discuss any alternative uses of quetiapine with your healthcare provider.
Quetiapine is available in the following dosage forms:
Quetiapine is a prescription medication. You must have a valid prescription from a licensed healthcare provider to obtain it.
The use of quetiapine can lead to various side effects in some individuals.
Common mild side effects of quetiapine use include:
More severe side effects include:
If you experience any severe or concerning side effects while taking quetiapine, contact your healthcare provider right away.
Inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with quetiapine. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with quetiapine.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using quetiapine with your healthcare provider.
Take quetiapine exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment.
Your provider may direct you to avoid alcohol while taking quetiapine, as it can increase the risk of side effects.
Quetiapine can cause drowsiness. Do not drive or operate machinery until you know how this medication affects you.
Complete the full course of treatment, even if you feel better, to ensure the medication's effectiveness in managing your symptoms.
In case of a quetiapine overdose, seek medical attention immediately. Symptoms of overdose may include severe drowsiness, dizziness, fainting, or rapid heartbeat. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.
Quetiapine is available in the following forms:
The typical starting dose of quetiapine varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.
For schizophrenia:
For bipolar disorder, depressive episode:
For bipolar disorder, acute mania:
The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history and your response to the medication.
Quetiapine should be taken as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.
If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.
If you miss a dose of quetiapine, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not double the dose to make up for a missed one.
Take quetiapine around the same time every day to maintain a consistent amount of medication in your body.
Continue taking quetiapine as prescribed by your healthcare provider, even if you start feeling better. It's important to keep taking the medication as directed to manage your condition effectively.
Do not suddenly stop taking quetiapine; this can cause withdrawal symptoms and a return of your symptoms.
If you have any concerns or questions about your medication, discuss them with your healthcare provider for medical advice and recommendations.
Store quetiapine according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from light and moisture. Ensure the container is tightly closed and out of reach of children.
Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.