Get a Rybelsus (semaglutide) prescription online for type 2 diabetes and/or weight loss

Rybelsus (semaglutide) is an incretin mimetic medication used to help patients with weight loss. Book a visit with an online weight loss specialist on Sesame to discuss whether or not Rybelsus (semaglutide) is right for you.

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Product Overview

Rybelsus (semaglutide)

  • What is Rybelsus (semaglutide)?
    Rybelsus is a prescription drug used to treat type 2 diabetes. Rybelsus is the brand name for semaglutide, which belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. It decreases your body’s blood glucose levels and increases its response to the hormone insulin to get your type 2 diabetes under control. Not only does semaglutide help manage blood sugar levels, but it can also help patients with type 2 diabetes reduce their risk of heart attack, stroke, and death.

    Rybelsus is prescribed in conjunction with other treatment measures such as exercise and dietary changes to help patients lose weight and prevent serious complications caused by diabetes. Rybelsus is prescribed in the form of a tablet to be taken orally. Other brand names for semaglutide include Wegovy and Ozempic, which are prescribed in the form of a subcutaneous injection (an injection under the skin).

    Talk to your health care provider about whether or not Rybelsus (semaglutide) is right for you.

  • What are the common side effects of Rybelsus (semaglutide)?
    Rybelsus (semaglutide) has been shown to cause some side effects. Talk to your health care provider if these adverse reactions do not go away within a few days.

  • Common side effects reported from Rybelsus (semaglutide) use include:

    ·Nausea
    ·Vomiting
    ·Diarrhea
    ·Abdominal pain
    ·Constipation
    ·Decreased appetite
    ·Heartburn
    ·Burping

This is not a complete list of all possible side effects caused by Rybelsus (semaglutide).

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Medically Reviewed By Dr. Allison Edwards, MD

Frequently asked questions about Rybelsus (semaglutide)

Rybelsus is a prescription drug used to treat type 2 diabetes. Rybelsus is the brand name for semaglutide, which belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. It decreases your body’s blood glucose levels and increases its response to the hormone insulin to get your type 2 diabetes under control. Not only does semaglutide help manage blood sugar levels, but it can also help patients with type 2 diabetes reduce their risk of heart attack, stroke, and death.

Rybelsus is prescribed in conjunction with other treatment measures such as exercise and dietary changes to help patients lose weight and prevent serious complications caused by diabetes. Rybelsus is prescribed in the form of a tablet to be taken orally. Other brand names for semaglutide include Wegovy and Ozempic, which are prescribed in the form of a subcutaneous injection (an injection under the skin).

Rybelsus is prescribed as a treatment for type 2 diabetes. Diabetes is a chronic condition in which the body does not produce insulin, a hormone that controls the amount of sugar in the blood and helps cells to absorb glucose (the sugar that our bodies use for energy). Without normal insulin levels, blood sugar levels can either become too high (hyperglycemia) or too low (hypoglycemia). Diabetes can lead to heart disease, kidney disease, eye damage, nerve damage, and skin conditions, among other complications.

Type 2 diabetes can be caused by obesity, poor diet, and lack of exercise, and occurs when the pancreas produces insulin, but the body becomes resistant to its effects. About 90% of people who have diabetes have type 2 diabetes. While both type 1 and type 2 diabetes may begin during childhood, type 2 diabetes is more common among adults, especially in obese individuals.

Rybelsus cannot treat type 1 diabetes, which is an autoimmune condition that occurs when your body attacks your pancreas with antibodies (causing the organ to stop producing insulin). It commonly appears during childhood and has no cure – although genetics and environment are thought to play a role in its development.

Rybelsus is also used to treat obesity, nonalcoholic steatohepatitis (NASH), and those who are overweight with comorbidity.

Rybelsus is classified as a GLP-1 agonist or GLP-1 receptor agonist, which are a category of antidiabetes medications that acts like incretin hormones (hormones released by the pancreas to stimulate a decrease in blood glucose levels). Rybelsus binds to incretin receptors, performing the same action as incretin hormones – essentially stimulating the release of glucose-dependent insulin. This helps your body metabolize blood sugar, which keeps glucose levels in check.

Rybelsus has been shown to cause some mild side effects. If these adverse effects do not go away within a few days, talk to your healthcare provider. Common side effects include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Constipation
  • Decreased appetite
  • Heartburn
  • Burping

This is not a complete list of possible adverse effects.

If you experience an unexplained rash, swelling, stomach pain, difficulty breathing, decreased urination, changes in vision, or itchy skin while taking Rybelsus, seek medical attention immediately. These are early signs of a potentially serious adverse reaction to the medication reaction.

Talk to your healthcare provider about any medication you are currently taking, or any medical conditions you have been previously diagnosed with before starting treatment with Rybelsus.

Rybelsus comes in the form of an oral tablet which is typically taken once a day on an empty stomach with a sip of water. You should take the tablet 30 minutes before you eat, drink, or take any other medications. However, you should take the medication exactly as prescribed by your healthcare provider. Do not discontinue or increase your Rybelsus dosage without consulting your provider first. If you begin to experience adverse side effects while taking this medication, like those listed above, inform your provider right away.

You should store your medication in a closed container at room temperature, away from extreme heat, extreme cold, moisture, and direct light, and keep it out of the reach of children.

Good news! If deemed clinically appropriate, providers on Sesame can write a prescription for Rybelsus to be picked up near you – often within the same day! Simply talk to a clinician and get your online doctor prescription or refill ordered right away for fast and convenient pickup from a pharmacy of your choice. Note that all prescriptions are at the discretion of your healthcare provider.

Rybelsus (semaglutide) costs usually costs between $800-$1000 without insurance. If you have insurance, book a video weight loss consult with an online weight loss doctor to determine if your prescription can be covered by your healthcare plan.

Rybelsus is currently only available via prescription. This means a licensed healthcare provider must authorize the use of this drug.

Looking for a prescription? Providers on Sesame can write a prescription – or refill an existing one – during a virtual or in-person visit. Depending on the medication, you can arrange for same-day pickup at a pharmacy near you or order the medication to be delivered to your door. Book an online consultation with a licensed provider on Sesame today to determine whether or not Rybelsus is right for you.

Note that all prescriptions are at the discretion of your healthcare provider. Providers on Sesame cannot prescribe controlled substances.

Rybelsus (semaglutide) usually costs about $900 without insurance. If you have insurance, you can book a video weight loss program to discuss treatment options with a licensed health care provider. Rybelsus can be prescribed during these appointments, if deemed appropriate by your provider. If you receive a Rybelsus prescription during your weight loss appointment, you may be eligible to have part of your visit and your medication covered by your insurance network. Our video weight loss program works with insurance to help cover the cost of your treatment.

Note that all prescriptions are at the discretion of your health care provider. A video weight loss appointment does not guarantee a Rybelsus prescription.

No, there are currently no generic alternatives to Rybelsus (semaglutide). Although there are other semaglutide medications (Wegovy, Ozempic) on the market, all GLP-1 agonist drugs are available only as brand-name products.

If you need assistance with navigating your options and determining the best GLP-1 agonist for your weight loss or type 2 diabetes management, schedule an appointment with an online weight loss doctor on Sesame to discuss what's best for you.

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