Scopolamine

Drug Information

Medically reviewed by Jessica Swirble, PharmD
Last updated on April 2, 2025

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Quick facts

• Brand Name: Transderm Scop
• Generic Name: Scopolamine
• Uses: Motion Sickness, Nausea and Vomiting
• Drug Class: Anticholinergic
• Availability: Prescription required for both transdermal patches
• Generic Status: Yes
• Controlled Substance: No

What is scopolamine?

Scopolamine is a medication commonly used to prevent motion sickness and reduce nausea and vomiting associated with certain medical conditions or treatments. It belongs to a class of drugs known as anticholinergics.

How does scopolamine work?

Scopolamine works by blocking the action of acetylcholine, a neurotransmitter in the brain that controls nausea and vomiting. By inhibiting the effects of acetylcholine, scopolamine helps alleviate symptoms of motion sickness and related nausea.

What conditions does scopolamine treat?

Scopolamine is primarily used to treat:

1. Motion Sickness: It is effective in preventing motion sickness symptoms such as nausea, vomiting, and dizziness during travel by boat, car, airplane, or other modes of transportation.

2. Nausea and Vomiting: Scopolamine is also prescribed to reduce nausea and vomiting caused by surgery, chemotherapy, or other medical procedures.

How do I use scopolamine?

The most common form of scopolamine is a patch applied behind the ear, usually several hours before travel or as directed by your healthcare provider. The patch is designed to release scopolamine slowly into the bloodstream over several days, providing continuous relief from motion sickness.

Follow your healthcare provider's instructions carefully regarding the dosage, timing, and duration of scopolamine use. Do not exceed the recommended dose without consulting your doctor.

How long until I start feeling better?

The onset of action for scopolamine can vary depending on the form used and individual response. For transdermal patches, it may take several hours to a day to experience the full effects. Oral tablets may act more quickly, usually within 30 minutes to an hour after ingestion. It's important to use scopolamine as directed and continue treatment for the prescribed duration to maintain its effectiveness.

Are there any other uses for scopolamine?

While scopolamine is primarily indicated for motion sickness and nausea/vomiting, healthcare providers may occasionally prescribe it off-label for other conditions. Discuss any alternative uses of scopolamine with your doctor.

Dosage forms of scopolamine

Scopolamine is available as a transdermal patch for motion sickness.

Generic versions of scopolamine are available under various brand names.

Scopolamine is a prescription medication. You will need a valid prescription from a healthcare provider to obtain this medication.

Side Effects and Precautions for Scopolamine

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What are the side effects of scopolamine?

The use of scopolamine, whether in transdermal patch or oral tablet form, can lead to various side effects in some individuals.

Common mild side effects of scopolamine use include:

• Dry mouth
• Drowsiness
• Dizziness
• Blurred vision
• Constipation
• Urinary retention (difficulty urinating)
• Dry skin or flushing at the patch site
• Dilated pupils (mydriasis)

More severe side effects of scopolamine use can include:

• Allergic reactions: Such as rash, itching, swelling of the face, lips, or throat, difficulty breathing
• Rapid heartbeat (tachycardia)
• Confusion or hallucinations
• Agitation or restlessness
• Memory problems or disorientation

If you experience any severe side effects while using scopolamine, seek medical attention immediately.

What should I tell my healthcare provider before using scopolamine?

Before using scopolamine, it's important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with scopolamine.

Tell your provider if you are taking the following medications or supplements:

• Other anticholinergic medications
• Sedatives or tranquilizers
• Antidepressants
• Antihistamines
• Medications for Parkinson's disease
• Herbal supplements like valerian root or others that may cause drowsiness or sedation

Additionally, mention any medical conditions you have, such as:

• Glaucoma or other eye problems
• Enlarged prostate (benign prostatic hyperplasia)
• Urinary retention issues
• Heart conditions or high blood pressure
• Liver or kidney problems
• Seizures
• Gastrointestinal disorders
• Pulmonary disease
• Psychiatric disorders
• Pregnancy, planning to become pregnant, or breastfeeding

Discuss with your healthcare provider any specific instructions or precautions related to your use of scopolamine.

Are there any other special instructions I should follow?

For transdermal patchs:

• Follow the instructions provided with your medication regarding dosage and administration.
• Avoid driving or operating machinery if you experience drowsiness or blurred vision while using scopolamine.
• Drink plenty of fluids to prevent dry mouth and constipation, especially with prolonged use.
• Remove the transdermal patch as directed and dispose of it properly.
• Store scopolamine patches away from heat and moisture, following storage guidelines provided with the medication.

What should I do in case of an overdose?

In case of an overdose of scopolamine, seek medical attention immediately. Symptoms may include severe drowsiness, confusion, rapid heartbeat, or difficulty breathing. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.

Proper Use & Dosage Information for Scopolamine

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How should scopolamine be used?

Scopolamine is available in different forms for different conditions:

• Transdermal patches: For motion sickness prevention and treatment.

For Transdermal Patches:

1. Patch Application:

   • Apply the patch behind your ear as directed by your healthcare provider.
   • Clean and dry the area before application.
   • Press the patch firmly in place and smooth out any wrinkles.
   • Wash your hands after handling the patch to avoid accidental contact with your eyes or mouth.

2. Patch Duration:

   • Follow the prescribed duration for wearing the patch. Some patches need to be replaced every 3 days.
   • Remove the old patch before applying a new one.

If you have any questions about your dosage or how to take this medication, contact your healthcare provider or pharmacist. If you want to talk to a provider right away, consider booking an online doctor appointment on Sesame to discuss your concerns.

What should I do if I miss a dose of scopolamine?

If you miss a dose of scopolamine take or apply the missed dose as soon as you remember. If it's nearly time to apply the next patch, skip the missed dose and continue with your regular schedule.

Do not take or apply a double dose to make up for a missed one.

What should I do if I'm feeling better?

Continue using scopolamine as prescribed, even if your symptoms improve. Abruptly stopping may lead to a return of symptoms or worsening of your condition. Follow your provider's instructions regarding the duration of treatment.

How should I store scopolamine?

Store scopolamine transdermal patches at room temperature, away from moisture and heat. Keep this medication out of reach of children.

Follow the storage instructions provided by your healthcare provider or pharmacist.