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Semaglutide

Common Brand Names: Ozempic, Rybelsus, Wegovy

Proper Use & Dosage Information

Medically reviewed by Jessica Swirble, PharmD
Last updated on 5/16/2024

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What is the typical starting dose for semaglutide?

Semaglutide is available in the following forms:

  • Injectable solution (Ozempic): 0.25 mg, 0.5 mg, 1 mg, and 2 mg pre-filled pens
  • Oral tablets (Rybelsus): 3 mg, 7 mg, 14 mg
  • Injectable solution for weight management (Wegovy): starting at 0.25 mg, increasing to 2.4 mg

The typical starting dose of semaglutide varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is important to follow your healthcare provider's instructions regarding dosage and administration.

For type 2 diabetes, the typical starting dose may be:

  • Injectable (Ozempic): 0.25 mg once weekly for the first four weeks, then increasing to 0.5 mg once weekly.
  • Oral tablets (Rybelsus): 3 mg once daily for 30 days, then increasing based on tolerance and blood sugar control.

For weight management:

  • Injectable (Wegovy): 0.25 mg once weekly for the first four weeks, gradually increasing over several months to 2.4 mg once weekly.

The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history, current medications, and response to the medication.

Semaglutide should be taken exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.

If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.

What should I do if I miss a dose of semaglutide?

If you miss a dose of semaglutide, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Maintain a consistent dosing schedule to ensure the effectiveness of semaglutide in managing your condition.

What should I do if I'm feeling better while taking semaglutide?

Continue taking semaglutide as prescribed by your healthcare provider, even if you start feeling better. Do not stop the medication abruptly without consulting your provider, as it may lead to a recurrence of symptoms or other complications.

Complete the full course of treatment as directed to minimize the risk of relapse.

If you have any concerns or questions about your medication, discuss them with your healthcare provider for personalized guidance and recommendations.

How should I store semaglutide?

Store semaglutide according to the instructions provided by your healthcare provider or pharmacist. Keep it in the refrigerator; do not freeze. Protect it from light, and do not use it if the solution changes color or contains particles. Ensure the container is tightly closed and out of reach of children.

Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.