Medically reviewed by Jessica Swirble, PharmD
Last updated on April 17, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Amiodarone is an antiarrhythmic medication used to treat various irregular heartbeats (arrhythmias) including ventricular fibrillation and ventricular tachycardia (VT). It works by affecting the electrical activity in the heart to help maintain a regular heartbeat.
Amiodarone is used to treat various types of arrhythmias. Arrhythmias are abnormal heart rhythms that can pose life-threatening complications.
Amiodarone works by affecting the electrical signals in the heart, specifically targeting abnormal rhythms and helping to restore a normal heartbeat. It belongs to the class III antiarrhythmic agents and has multiple mechanisms of action that contribute to its effectiveness in managing arrhythmias.
Amiodarone is usually taken orally with or without food, as directed by your healthcare provider. The dosage and duration of treatment depend on the type and severity of the arrhythmia.
Amiodarone can be taken with food if it helps prevent an upset stomach, dosage should be consistent: either always take amiodarone with food or always without.
Follow the prescribed dosage and schedule strictly. Do not stop taking amiodarone suddenly without consulting your healthcare provider, as it may lead to worsening arrhythmias or other complications.
The time it takes to see improvements in arrhythmias can vary depending on the type of arrhythmia, its severity, and individual response to treatment. Some patients may experience improvements relatively quickly, while others may require longer periods to achieve stable heart rhythms.
Continue taking amiodarone as prescribed even if you feel better. Abruptly stopping the medication can result in the recurrence of arrhythmias.
While amiodarone is primarily used for treating arrhythmias, healthcare providers may sometimes prescribe it off-label for other heart-related conditions or purposes, such as:
Discuss any alternative uses of amiodarone with your healthcare provider.
Amiodarone is available in the following dosage forms:
Generic versions of amiodarone are available under various brand names.
Amiodarone is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this medication.
The use of amiodarone can lead to various side effects in some individuals.
Common mild side effects of amiodarone use include:
More severe side effects of amiodarone use can include:
If you experience any severe or concerning side effects while taking amiodarone, contact your healthcare provider promptly.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with amiodarone. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with amiodarone.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using amiodarone to assess potential risks and benefits.
Take amiodarone exactly as prescribed by your healthcare provider. Do not skip doses or stop the medication prematurely, even if you start feeling better.
Amiodarone should be taken with food to improve absorption and reduce stomach upset.
Avoid excessive exposure to sunlight or tanning beds while taking amiodarone, as it can increase sensitivity to sunlight and lead to sunburn or skin damage.
Do not drink grapefruit juice or consume grapefruit products while taking amiodarone, as they can interact with the medication and increase the risk of side effects.
Store amiodarone at room temperature, away from moisture and heat. Keep it out of reach of children.
In case of an amiodarone overdose, seek medical attention immediately. Symptoms of overdose may include severe dizziness, fainting, irregular heartbeat, or difficulty breathing. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.
Amiodarone is available in the following forms:
The typical starting dose of amiodarone varies depending on the condition being treated and individual patient factors. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.
For ventricular fibrillation (VFib) or ventricular tachycardia (VT), typical starting doses may include:
For other arrhythmias or specific cardiac conditions, the starting dose and regimen may vary. Your healthcare provider will determine the most appropriate dose based on your medical history, current medications, and response to treatment.
Amiodarone should be taken exactly as prescribed by your healthcare provider. Do not adjust your dose or stop taking the medication without consulting your provider.
If you have any questions about your dosage, contact your healthcare provider. If you want to talk to a provider right away, book an online doctor appointment on Sesame to discuss your concerns.
If you miss a dose of amiodarone, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take extra doses to make up for missed ones.
It is important to maintain a consistent dosing schedule to achieve optimal therapeutic effects.
Continue taking amiodarone as prescribed by your healthcare provider, even if you start feeling better. Do not stop taking the medication without consulting your provider, as sudden discontinuation can lead to rebound arrhythmias or other complications.
Store amiodarone according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from moisture, heat, and light. Ensure the container is tightly closed and out of reach of children.
Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist.