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Product Overview

Amiodarone (generic Pacerone)

  • What is amiodarone?
    Amiodarone (generic Pacerone) is a prescription drug used to treat an irregular heartbeat. It can address serious and life-threatening heart rates by helping your heart find a more consistent, steady rhythm.

    Talk to your doctor before starting amiodarone therapy. If you are taking any other medication, let your doctor know right away, as some drug interactions may cause serious side effects. Amiodarone is not recommended for women who are breastfeeding, or for patients taking medication to treat hepatitis, liver disease, lung disease, or thyroid problems.

  • What are common side effects of amiodarone?
    While adverse reactions to amiodarone are uncommon, some patients who take the drug experience mild side effects including slow heart rate, weight loss, constipation, low blood pressure, nausea, vomiting, fatigue, and decreased libido.

    Rare, more serious adverse events have been known to occur, such as lung infiltrates, abnormal heart rhythms, congestive heart failure, elevated liver enzymes, visual disturbances, photosensitivity, blue skin discoloration, and thyroid problems. Contact your doctor or provider if you are experiencing these symptoms.

    This is not a complete list of side effects. For more information about adverse effects you may experience while taking amiodarone, please visit the National Institutes of Health’s DailyMed webpage.

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Medically Reviewed by Dr. Allison Edwards, MD

Frequently asked questions about Amiodarone

What is Amiodarone?

Amiodarone (generic for Pacerone or Cordarone) is a prescription medication used to treat cardiac arrhythmia - also known as irregular heartbeat. As an antiarrhythmic drug, amiodarone may also be used to treat fast heart rate (ventricular tachycardia) in adults who have not responded to other irregular heartbeat medications. Amiodarone addresses serious and life-threatening arrhythmias by blocking electrical signals that may trigger an irregular heartbeat. This helps maintain a consistent and steady heart rhythm.

Amiodarone can be taken orally or via injection. It is usually administered as an injection following an instance of heart failure and prescribed orally to treat life-threatening arrhythmia. Amiodarone injections are never prescribed for at-home treatment, and oral amiodarone is only prescribed for life-threatening cases of arrhythmia or tachycardia.

What is amiodarone used to treat?

Amiodarone has been approved by the FDA to treat a range of conditions related to cardiac arrhythmia. These include ventricular arrhythmia, ventricular fibrillation/tachycardia, and atrial fibrillation - an irregular rhythm in the heart's main arterial chambers.

What are the most common side effects of amiodarone?

While there are some side effects associated with amiodarone, it is important to note that your doctor has prescribed this medication because its central benefit - bringing your irregular heartbeat under control - outweigh any possible adverse reactions.

Common side effects of amiodarone include:

  • Hypothyroidism
  • Hyperthyroidism
  • Bycardia
  • Weight loss
  • Constipation
  • Hypotension
  • Nausea
  • Vomiting
  • Fatigue
  • Decreased libido

Amiodarone can cause serious side effects that may require you to stop taking the drug. If you begin to notice more serious adverse side effects, or if the side effects listed above persist for more than a few days, talk to a health care provider right away.

Side effects are more likely if you have been taking amiodarone for an extended period of time.

Talk to your doctor before starting amiodarone therapy. If you are taking any other medication, let your doctor know right away, as some drug interactions may cause serious side effects. Amiodarone is not recommended for women who are breastfeeding, or for patients taking medication to treat hepatitis, liver disease, lung disease, or thyroid problems.

Amiodarone is only prescribed to treat life-threatening arrhythmia. Your doctor will help determine whether or not amiodarone therapy is the right treatment plan for you. Do not stop taking amiodarone without consulting your doctor, and do not exceed the dosage prescribed by your doctor.

This is not a complete list of side effects associated with amiodarone. For more information on adverse effects you may experience while taking amiodarone, visit the National Institutes of Health’s DailyMed webpage.

How does amiodarone work?

Amiodarone is an antiarrhythmic medication belonging to a family of drugs that treat irregular heartbeat and related conditions. Amiodarone works by settling the heart's rhythm and allowing it to pump at a more regular cadence.

Potassium channels can interfere with the heart's natural rhythm, particularly during a process called "repolarization." Amiodarone works by blocking these channels, resulting in a slower, more consistent heartbeat.
Amiodarone is commonly given to patients who have just experienced heart failure, or patients who experience persistent life-threatening arrhythmia (irregular heartbeats). While amiodarone therapy may produce serious side effects, amiodarone can be life-saving if administered and prescribed properly.

What is the typical starting dose of amiodarone?

Amiodarone dosage usually starts around 800-1600 mg per day, depending on the age and health history of the patient. Once your arrhythmia is is under control - or you begin to experience serious side effects - your doctor may lower your dosage to 600-800 mg per day. After a month, if amiodarone therapy is still needed, your dosage may be lowered to 400 mg per day.

Can I get amiodarone over-the-counter?

Amiodarone is currently only available via prescription. This means the use of this drug must be authorized by a licensed health care provider.

Providers on Sesame can write a prescription – or refill an existing one – during a virtual or in-person visit. Depending on the medication, you can arrange for same-day pickup at a pharmacy near you or order the medication to be delivered to your door for just $5. Book an online consultation with a real, licensed provider on Sesame today to determine whether or not amiodarone is right for you.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

Can I get amiodarone online?

Yes! Sesame offers a fully integrated prescription service, which means you can get the medication you need delivered right to your door, starting at just $5 a month.

Talk to a provider on Sesame and get your online doctor prescription or refill ordered right away for fast and convenient pickup from a pharmacy of your choice.

Note that all prescriptions are at the discretion of your clinician.

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