Medically reviewed by Jessica Swirble, PharmD
Last updated on 6/18/2024

Drug Information | Side Effects | Use & Dosage | Request a Prescription

Amitriptyline is available in the following forms:

• Oral tablets (10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 150 mg)
  
  

The typical starting dose of amitriptyline varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.

For depression:

• Adults: The typical starting dose is 75 mg per day daily, split into divided doses. The maintenance dose of amitriptyline is 40-100 mg per day, split into divided doses.
  
• Alternative doses for adults: 50-100 mg once daily, taken at bedtime.
  
  

The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history and your response to the medication.

Amitriptyline should be taken as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.

If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.

If you miss a dose of amitriptyline, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not double the dose to make up for a missed one.

Take amitriptyline around the same time every day to maintain a consistent amount of medication in your body.

Continue taking amitriptyline as prescribed by your healthcare provider, even if you start feeling better. It's important to keep taking the medication as directed to manage your condition effectively.

Do not suddenly stop taking amitriptyline; this can cause withdrawal symptoms and a return of your symptoms.

If you have any concerns or questions about your medication, discuss them with your healthcare provider for medical advice and recommendations.

Store amitriptyline according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from light and moisture. Ensure the container is tightly closed and out of reach of children.

Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.