Medically reviewed by Jessica Swirble, PharmD
Last updated on March 27, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Buspirone is a medication prescribed to treat anxiety disorders, including generalized anxiety disorder (GAD). It is classified as an azapirone, which is a relatively new type of medication that works by affecting certain neurotransmitters in the brain.
Buspirone is primarily used to treat anxiety disorders or the symptoms of anxiety.
It may also be prescribed off-label for other anxiety-related conditions as determined by your healthcare provider.
Buspirone works by affecting the neurotransmitters serotonin and dopamine in the brain. It has a unique mechanism of action compared to other anxiolytics, helping to reduce anxiety symptoms without causing sedation or dependence.
Buspirone is typically taken orally, usually two times a day. It can be taken with or without food. However, you should stay consistent: either always take it with food or always take it without food. Take buspirone consistently to maintain steady levels in your bloodstream. Your healthcare provider will determine the appropriate dosage and dosing schedule based on your condition and response to treatment.
Consult your healthcare provider for specific instructions on how to take citalopram properly.
The time it takes to experience improvements in your anxiety symptoms while taking buspirone can vary. Some individuals may notice changes within a few days, while it may take several weeks for others to feel the full benefits. It's crucial to continue taking buspirone as prescribed, even if you start feeling better, to ensure the best outcome.
While buspirone is primarily used for generalized anxiety disorder (GAD), healthcare providers may sometimes prescribe it off-label for other conditions, including:
Discuss any alternative uses of buspirone with your healthcare provider.
Buspirone is available in the following dosage forms:
Generic versions of buspirone are available under various brand names.
Buspirone is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this drug.
The use of buspirone has been shown to cause side effects in some patients.
Common mild side effects of buspirone use include:
More severe side effects include:
Seek medical attention immediately if you experience any severe symptoms while taking buspirone. If you experience mild side effects that become severe or do not go away after a few days, speak to a healthcare provider right away.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with buspirone. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with this drug.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using buspirone to assess potential risks and benefits.
Buspirone can be taken with or without food. However, to maintain a consistent level in your bloodstream, try to take it at the same time each day. You should either always take buspirone with food or always without food.
Avoid alcohol while taking buspirone, as it may exacerbate certain side effects like drowsiness and dizziness.
Avoid consuming grapefruit or grapefruit juice while taking buspirone, as it can interfere with the medication's effectiveness.
Your healthcare provider may suggest regular monitoring of your blood pressure and heart rate while you are taking buspirone, particularly during the initial months of treatment.
Your healthcare provider will provide specific instructions regarding the use of buspirone with food, beverages, and other medications. It's essential to follow their guidance to ensure the effectiveness of the treatment and minimize the risk of side effects.
The symptoms of a buspirone overdose include:
If you experience any of these symptoms, call the poison control helpline at 1-800-222-1222. If an individual has collapsed, is having seizures, or is unresponsive, call 9-1-1 immediately.
Buspirone is available in various strengths, including:
The typical starting dose of buspirone for anxiety can vary depending on factors such as the severity of symptoms, your age, other medical conditions, and how you respond to the medication. It's essential to follow your healthcare provider's instructions regarding dosage and administration carefully.
For most adults with anxiety, the typical starting dose of buspirone may be:
Your healthcare provider may start with a lower dose, such as 5 mg, especially for older adults or those with certain medical conditions. The dose may then be gradually increased up to a maximum of 60 mg per day, taken in divided doses.
Buspirone should be taken with or without food, but it's important to take it consistently at the same time(s) each day.
Your healthcare provider will monitor your response to the medication and may adjust the dose as needed.
If you have any questions about your dosage, contact your healthcare provider. If you want to talk to a provider right away, book an online doctor appointment on Sesame to discuss your concerns.
If you miss a dose, take it as soon as you remember it. If it's almost time for another dose of buspirone, skip the missed dose and take your next dose as scheduled. Do not take or apply a double dose of buspirone.
Do not stop taking buspirone suddenly without consulting your healthcare provider. Abruptly stopping the medication can lead to withdrawal symptoms or a relapse of your condition. Your doctor may need to gradually decrease your dose to avoid these effects.
Store buspirone as directed by your healthcare provider or pharmacist. Proper storage is essential to maintain the medication's effectiveness. Buspirone should be stored at room temperature, away from excessive heat, light, and moisture.
Keep the medication out of the reach of children and ensure that the container is tightly closed.