Medically reviewed by Jessica Swirble, PharmD
Last updated on 6/6/2024

Drug Information | Side Effects | Use & Dosage | Request a Prescription

The use of celecoxib can lead to various side effects in some individuals.

Common mild side effects of celecoxib use include:

• Gas
  
• Bloating
  
• Diarrhea
  
• Constipation
  
• Nausea
  
• Vomiting
  
• Dizziness
  
• Abdominal pain
  
• Altered taste
  
• Cold symptoms such as a runny nose or sore throat
  
  

More severe side effects of celecoxib use can include:

• Weight gain
  
• Skin rash
  
• Hives
  
• Swelling in the hands, feet, or ankles
  
• Nausea
  
• Flu-like symptoms
  
• Difficulty breathing or swallowing
  
• Changes in heartbeat
  
• Chest pain
  
• High blood pressure
  
• Pale skin
  
• Yellowing of the skin or eyes
  
• Vomiting
  
• Blood in stool
  
  

If you experience any severe or concerning side effects while taking celecoxib, contact your healthcare provider right away.

Inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with celecoxib. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with celecoxib.

Tell your provider if you are taking these medications or supplements:

• ACE inhibitors
  
• Angiotensin receptor blockers
  
• Beta-blockers
  
• Digoxin
  
• Diuretics
  
• Fluconazole
  
• Lithium
  
• Methotrexate
  
• Blood thinners
  
• Other NSAIDs
  
• Aspirin or salicylates
  
  

You should also mention medical conditions such as:

• Asthma
  
• Nasal polyps
  
• Stomach ulcers
  
• Heart disease
  
• High blood pressure
  
• Bleeding disorders
  
• Liver disease
  
• Kidney disease
  
• Alcohol or tobacco use
  
  

If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using celecoxib with your healthcare provider.

Take celecoxib exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment.

Your provider may direct you to avoid alcohol and smoking while taking celecoxib, as they can increase your risk of stomach bleeding.

Complete the full course of treatment, even if you feel better, to ensure the medication's effectiveness in managing your condition.

In case of a celecoxib overdose, seek medical attention immediately. Symptoms of overdose may include severe stomach pain, nausea, vomiting, drowsiness, or difficulty breathing. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.