Doxylamine and pyridoxine, marketed under the brand name Diclegis, is a prescription medication used to treat nausea and vomiting during pregnancy, commonly referred to as morning sickness. It combines an antihistamine (doxylamine) and a form of vitamin B6 (pyridoxine). This medication is specifically formulated to provide relief from the symptoms of morning sickness in pregnant individuals.

Doxylamine and pyridoxine is available under the brand names Bonjesta and Diclegis or in its generic form.

This medication can only be obtained with a prescription, meaning you must have a written prescription from a licensed healthcare provider to purchase it.

Doxylamine and pyridoxine is primarily prescribed for the treatment of nausea and vomiting during pregnancy, which is commonly experienced during the first trimester. Morning sickness can significantly impact the well-being of pregnant individuals and affect their ability to maintain proper nutrition and hydration.

Doxylamine and pyridoxine is specifically formulated to alleviate these symptoms and improve the quality of life for pregnant individuals experiencing morning sickness.

Doxylamine and pyridoxine works through the combination of its two active ingredients:

Doxylamine: This antihistamine helps reduce nausea and vomiting by blocking the action of histamine, a neurotransmitter associated with these symptoms.

Pyridoxine: Pyridoxine is a form of vitamin B6, a nutrient that helps control nausea and vomiting, particularly during pregnancy. Studies have shown women who experience nausea and vomiting during pregnancy have lower levels of circulating Vitamin B6. Pyridoxine’s exact mechanism of action, however, is still unknown.

The combination of these two ingredients helps alleviate the symptoms of morning sickness.

The use of doxylamine and pyridoxine may lead to adverse side effects.

Mild side effects associated with doxylamine and pyridoxine may include:

• Drowsiness
  
• Dry mouth
  
• Dizziness
  
• Restlessness
  
• Headache
  
• Constipation
  
• Diarrhea
  
  

These side effects are generally mild and well-tolerated. However, if they persist or worsen, consult your healthcare provider.

More severe side effects include:

• Vision problems
  
• Urination problems
  
• Fast or irregular heartbeat
  
• Shortness of breath
  
• Confusion
  
• Seizures
  
• Muscle pain or weakness
  
  

If you experience any of these side effects or have concerns about them, consult your healthcare provider.

Before starting doxylamine and pyridoxine, inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with doxylamine and pyridoxine.

Specifically, tell your healthcare provider if you have a history of:

• Allergies to medications, especially antihistamines
  
• Asthma
  
• Glaucoma
  
• High blood pressure
  
• Kidney disease
  
• Liver disease
  
• Bladder neck obstruction
  
• Stenosing peptic ulcer or pyloroduodenal obstruction
  
  

If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using doxylamine and pyridoxine to assess potential risks and benefits.

The recommended dosing of doxylamine and pyridoxine may vary depending on individual needs and the severity of morning sickness. Your healthcare provider will determine the appropriate dosage for your situation.

Typically, doxylamine and pyridoxine is taken as an oral tablet. If necessary, your healthcare provider may adjust the dosage.

Do not exceed the recommended dosage unless directed by your healthcare provider.

If you miss a dose, take it as soon as possible. If it's nearly time for your next dose, skip the missed dose and take your regularly scheduled amount. Do not take a double dose of doxylamine and pyridoxine.

Doxylamine and pyridoxine is available by prescription only. A licensed healthcare provider must authorize the use of this drug.

Looking for a prescription? Providers on Sesame can assess your eligibility and prescribe doxylamine and pyridoxine if it's appropriate for your medical condition and needs. You can arrange for same-day pickup at your pharmacy, depending on the medication. Book an online consultation with a licensed provider on Sesame today to determine whether doxylamine and pyridoxine might be right for you.

Providers on Sesame are unable to prescribe controlled substances.

Note that all prescriptions are at the discretion of your healthcare provider. Sesame cannot guarantee that you will be provided a prescription after a video or in-person appointment.

Providers on Sesame can assist you with obtaining a prescription for doxylamine and pyridoxine, which you can pick up at a pharmacy near you, often on the same day. Don't wait to get your prescription filled—talk to a provider on Sesame today and streamline the process for convenient pickup from a pharmacy of your choice.

Please remember that the decision to prescribe Doxylamine and pyridoxine is at the discretion of your healthcare provider.