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Famotidine

Common Brand Names: Pepcid

Side Effects & Precautions

Medically reviewed by Jessica Swirble, PharmD
Last updated on 6/6/2024

Drug Information | Side Effects | Use & Dosage | Request a Prescription

What are the side effects of famotidine?

The use of famotidine can lead to various side effects in some individuals.

Common mild side effects of famotidine use include:

  • Headache
  • Dizziness
  • Diarrhea
  • Constipation

More severe side effects of famotidine use can include:

  • Confusion or hallucinations
  • Tiredness
  • Hives
  • Skin rash
  • Difficulty breathing or swallowing
  • Swelling
  • Hoarseness
  • Seizures
  • Rapid heartbeats
  • Muscle pain or weakness

If you experience any severe or concerning side effects while taking famotidine, contact your healthcare provider right away.

What should I tell my healthcare provider before using famotidine?

Inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with famotidine. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with famotidine.

Tell your provider if you are taking these medications or supplements:

  • Other heartburn medications
  • Antibiotics
  • Antifungals
  • Risedronate
  • Tizanidine

You should also mention medical conditions such as:

  • Kidney disease
  • Vitamin B12 deficiency
  • Stomach cancer
  • Long QT syndrome

If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using famotidine with your healthcare provider.

Are there any other special instructions I should follow?

Take famotidine exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment.

Your provider may direct you to avoid certain foods and beverages that can aggravate your condition, such as spicy foods, caffeine, and alcohol while taking famotidine.

Famotidine can cause dizziness or drowsiness. Because of this, you should not operate a motor vehicle or heavy machinery until you know how this medication affects you.

Complete the full course of treatment, even if you feel better, to ensure the medication's effectiveness in managing your condition.

What should I do in case of an overdose?

In case of a famotidine overdose, seek medical attention immediately. Symptoms of overdose may include severe dizziness, fainting, confusion, or unusual tiredness. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.