The most common side effects of fluticasone/salmeterol combination include:
- runny nose
- sneezing
- sore throat or throat irritation
- sinus pain
- headache
- nausea
- vomiting
- diarrhea
- stomach pain
- muscle and bone pain
- dizziness
- weakness
- tiredness
- sweating
- tooth pain
- shaking of a part of your body that you cannot control
- sleep problems
Seek medical attention right away if you experience any of the following symptoms while taking fluticasone/salmeterol combination:
- coughing, wheezing, or chest tightness that begins soon after you inhale fluticasone/salmeterol
- hives
- rash
- swelling of the face, throat, tongue, lips, hands, feet, ankles, or lower legs
- choking or difficulty swallowing
- hoarseness
- noisy, high-pitched breathing
- pounding fast, or irregular heartbeat
- burning or tingling in the hands or feet
- white patches in the mouth
- fever, chills, and other signs of infection
This is not a complete list of adverse effects. Call your health care provider if symptoms are persistent or severe.
As with all prescription medication, be sure to inform the prescribing doctor about any medical conditions you have been previously diagnosed with, as well as any medication/ supplements you are currently taking before starting treatment with fluticasone/salmeterol. Fluticasone/salmeterol can interact with other forms of medication and substances, causing potentially serious side effects or life-threatening allergic reactions. Drug interactions can occur with antifungals, antibiotics, antidepressants, antivirals and beta-blockers among others.
In addition, let your doctor know if you are breastfeeding, pregnant or plan on becoming pregnant before starting treatment with this medication.