Insulin lispro has been shown to cause adverse side effects in some patients. If these reactions become severe or do not go away after a day or two, seek medical attention right away.
Mild side effects reported from insulin lispro use include:
- Irritation or redness at the injection site
- Skin thickening
- Congestion
- Runny nose
- Sore throat
- Fatigue
- Weight changes
- Constipation
More serious side effects include:
- Rash and itching
- Hives
- Shortness of breath
- Changes in heartbeat
- Muscle cramps
- Dramatic weight gain
- Swelling
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a possibly serious adverse reaction to this medication and require treatment right away.
As with all medication, inform your doctor of any medical conditions you are currently managing. Tell them about any and all medication, prescription drugs, and supplements you are taking before starting treatment with insulin lispro. Insulin lispro can interact with substances in the body, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any angiotensin-converting enzyme inhibitors (ACE), beta-blockers, cholesterol-lowering medication, HIV medication, diuretics, or replacement hormones you have been taking, as well as if you have recently been taking cyclosporine before you start taking insulin lispro. Be sure to mention any herbal products you are using.
Tell your doctor if you have had heart failure or low levels of potassium in the blood. You should also tell them if you have had heart, liver or kidney disease.
In addition, let your doctor know if you are planning to become pregnant, are pregnant, or are currently breastfeeding before starting treatment with this medication. Call your provider if you become pregnant while you are taking insulin lispro.