Get a naloxone prescription online for opioid overdose

Get convenient and affordable naloxone prescriptions available for same-day pickup at your local pharmacy. Talk to a health care provider on Sesame to start treatment right away.

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Product Overview

Naloxone (Narcan)

  • What is naloxone?
    Naloxone, which is more commonly known by its brand name Narcan, is a medication that is used to rapidly reverse the effects of an opioid overdose. Naloxone is an opioid antagonist, which means that it binds to the opioid receptors in the central nervous system and blocks the action of opioids such as heroin, morphine, and prescription painkillers like oxycodone.

    Opioids can cause respiratory depression, a life-threatening health issue that decreases – to the point of eliminating – a person’s innate drive to breath and causes oxygen deprivation, coma, or even death if not addressed. Naloxone counteracts the dangerous respiratory depression that characterizes an overdose, allowing the individual to breathe normally again. Due to its critical role in combating the opioid crisis, naloxone has become an essential tool for first responders, healthcare professionals, and bystanders when treating an opioid overdose. However, it is important to note that naloxone is not a treatment for opioid use disorder.

    Naloxone is available both over-the-counter and as a prescription. It is sold in the form of an injectable solution, as a pre-filled auto-injector, and as a nasal spray (sold under the brand names Narcan and Kloxxado).

  • What are the common side effects of naloxone?
    Naloxone has been shown to cause some minor side effects. Talk to your health care provider if these adverse reactions do not go away within a few days.

  • Common side effects reported from naloxone use include:

    ·Headaches
    ·Joint pain
    ·Muscle pain

This is not a complete list of all possible side effects caused by naloxone.

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    Pay upfront and set up a visit with a real, quality provider on your schedule.

  • Same-day pickup
    Prescription sent to your local pharmacy during your appointment.

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1. Book a VisitFind quality doctors and specialists on your schedule. Read reviews, check availability, and book a same-day video appointment for as low as $37 at the touch of a button.
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3. Get A Prescription & SavePrescriptions are sent directly to your local pharmacy for same-day pickup.
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Medically Reviewed By Dr. Allison Edwards, MD

Frequently asked questions about naloxone

Naloxone, which is more commonly known by its brand name Narcan, is a medication that is used to rapidly reverse the effects of an opioid overdose. Naloxone is an opioid antagonist, which means that it binds to the opioid receptors in the central nervous system and blocks the action of opioids such as heroin, morphine, and prescription painkillers like oxycodone.

Opioids can cause respiratory depression, a life-threatening health issue that decreases – to the point of eliminating – a person’s innate drive to breath and causes oxygen deprivation, coma, or even death if not addressed. Naloxone counteracts the dangerous respiratory depression that characterizes an overdose, allowing the individual to breathe normally again. Due to its critical role in combating the opioid crisis, naloxone has become an essential tool for first responders, healthcare professionals, and bystanders when treating an opioid overdose. However, it is important to note that naloxone is not a treatment for opioid use disorder.

Naloxone is available both over-the-counter and as a prescription. It is sold in the form of an injectable solution, as a pre-filled auto-injector, and as a nasal spray (sold under the brand names Narcan and Kloxxado).

Naloxone is considered to be a safe harm-reduction measure by the medical community, as it does not cause harm if administered to someone who does not have opioids in their system and has minimal side effects. Common side effects of naloxone include headaches and joint or muscle pain, while less common side effects include discomfort in the nose, stomach ache, or dizziness.

Naloxone may also trigger symptoms of opioid withdrawal as it reverses the effects of opioids within the patient’s system. Opioid withdrawal symptoms may include:

  • Irritability
  • Body aches
  • Tearing
  • Diarrhea
  • Nausea
  • Fever
  • Chills
  • Goosebumps
  • Sneezing
  • Runny nose

    Seek medical attention if you experience any unusual symptoms or problems while using naloxone.

Be sure to inform the prescribing doctor or health care professional about any medical conditions you have been previously diagnosed with, as well as any medication/ supplements you are currently taking before starting treatment with naloxone.

Naloxone is sold as a pre-filled auto-injection or as a small, pre-filled nasal spray bottle with a nozzle and plunger.

To administer naloxone auto-injection, follow the printed instructions on the device label. The injection should be injected under the skin or into a muscle. It can be administered through clothing if necessary. You should administer another injection every 2 to 3 minutes until the patient responds or until emergency medical assistance arrives.

To administer naloxone nasal spray to someone who is overdosing, follow the instructions on the device and place the nozzle into the patient’s nostril, then press the plunger down to spray. It’s recommended that the spray is administered every 2 to 3 minutes, alternating nostrils, until the patient responds or until emergency medical assistance becomes available.

Naloxone should be administered to anyone who appears to be overdosing. Symptoms of an opioid overdose include the following:

  • Slowed or stopped breathing
  • Blue or purple lips or nails
  • Pinpoint pupils
  • Cold and clammy skin
  • Pale or ashen skin
  • Extreme sleepiness or unresponsiveness
  • Slow or irregular heartbeat
  • Choking or gurgling sounds

It is important to administer naloxone immediately if someone is displaying these symptoms or if an overdose is suspected. After you’ve administered Narcan, you should call 911 right away. If you’re unsure if someone is overdosing from a drug other than opioids, it is still best to administer Narcan since it does not have any impact on people who are not under the influence of opioids.

Naloxone should be stored in a closed container at room temperature, away from extreme heat, extreme cold, moisture, and direct light, and keep it out of the reach of children.

Although Sesame providers do not prescribe opioids or any other controlled substances virtually, they can prescribe Narcan as an overdose prevention measure. If you or a loved one have a history of opioid addiction or overdose or have been prescribed high-dose opioids and would like to discuss Narcan with a healthcare professional, you can book an appointment with a Sesame telehealth doctor and get the care you need.

Note that all prescriptions are at the discretion of your doctor.

While naloxone is approved for OTC sale as of March 29, 2023, Narcan's manufacturer estimates that it will be commercialized and widely available by late summer of 2023. In the meantime, it will continue to be available via prescription.

Looking for a prescription? Good news! Providers on Sesame can write a prescription – or refill an existing one – during a virtual or in-person visit. If you or a loved one has recently been prescribed high-dose opioids or is struggling with opioid addiction, book an online consultation with a real, licensed provider on Sesame today to determine whether or not naloxone is right for you.

Note that all prescriptions are at the discretion of your healthcare provider. Providers on Sesame cannot prescribe controlled substances.

Depending on the medication, some Sesame providers may require proof of a prior prescription before refilling it. Your provider may ask to see a picture of an old pill bottle or check for previous prescriptions from another Sesame provider. In some instances, your Sesame provider may also be able to access a national pharmacy system to see prescriptions from non-Sesame providers.

No. Clinicians on Sesame can prescribe a wide range of medications as treatment for infections, allergies, and other ailments (such as blood pressure medication). However, doctors and nurses on Sesame will not prescribe any medication listed as a controlled substance. This includes opioids and narcotics. Check out DEA.gov for a detailed list of medications that are listed as controlled substances.

Sesame does not accept insurance for provider appointments - however, you can pay with cash, credit, debit, or even your FSA or HSA card since visits and prescriptions on Sesame are considered health expenses.

However, Sesame clinicians can assist with insurance prior authorization specifically for patients who book a weight management service through Sesame’s online weight loss program.

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