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Propranolol

Common Brand Names: Inderal

Drug Information

Medically reviewed by Jessica Swirble, PharmD
Last updated on April 17, 2025

Drug Information | Side Effects | Use & Dosage | Request an Online Prescription

Quick facts:

  • Brand Name: Inderal
  • Generic Name: Propranolol
  • Uses: Treating high blood pressure, angina (chest pain), certain heart rhythm disorders, and reducing the risk of a second heart attack. Also used for preventing migraines and treating tremors and anxiety disorders.
  • Drug Class: Beta-blocker
  • Availability: Prescription only
  • Generic Status: Yes
  • Controlled Substance: No

What is propranolol?

Propranolol is a medication used to manage cardiovascular conditions primarily by slowing the heart rate and reducing blood pressure. It belongs to a class of medications known as beta-blockers, which work by blocking the effects of epinephrine and norepinephrine on the body's beta receptors, which helps to ease stress on the heart and blood vessels.

What conditions does propranolol treat?

Propranolol is used to treat a variety of conditions related to heart and blood vessel disorders.

This includes:

  • High blood pressure: Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems.
  • Angina: Reduces the frequency of chest pain from blocked or narrowed arteries.
  • Heart rhythm disorders: Helps to manage abnormal heart rhythms.
  • Migraine prevention: Reduces the frequency and severity of migraines.
  • Tremor: Helps to control shaking or trembling in part of the body.

How does propranolol work?

Propranolol belongs to a classification of medications known as beta-blockers. These medications work by blocking the transmission of certain nerve impulses. When stimulated, nerves release a chemical called epinephrine (also known as adrenaline). Adrenaline can cause blood vessels to tighten and narrow. Narrowed blood vessels make it more difficult for blood to be pumped through the body, leading to an increase in blood pressure.

By preventing epinephrine’s effect on blood vessels, propranolol keeps them relaxed and open. This reduces blood pressure and minimizes the risk of cardiac conditions such as heart attack, heart failure, and coronary artery disease.

It is important to note that propranolol is not a cure for high blood pressure, though it does help control it.

How do I take propranolol?

Propranolol is available in the following forms:

  • Oral tablets: Immediate-release and extended-release forms
  • Oral solution (liquid)

The dosage and length of treatment depend on the condition being treated, its severity, and how you tolerate the medication.

Follow your healthcare provider's instructions regarding dosage and schedule. Do not exceed the prescribed dose or duration of treatment without consulting your provider.

How long until I feel better?

The effectiveness of propranolol and the time it takes to notice improvement can vary among individuals. For conditions like hypertension or anxiety, some effects can be noticed shortly after starting the medication, but it may take a few weeks to achieve the full therapeutic effects.

Continue taking propranolol as prescribed even if you start feeling better. Do not abruptly stop the medication, as it may lead to a return of symptoms or exacerbation of heart conditions.

Are there any other uses for propranolol?

While propranolol is primarily used for treating high blood pressure, angina, certain heart rhythm disorders, and prevention of migraines, healthcare providers may sometimes prescribe it off-label for other conditions such as anxiety disorders, certain types of tremors, and prevention of secondary heart attacks.

Discuss any alternative uses of propranolol with your healthcare provider.

Dosage forms of propranolol

Propranolol is available in the following dosage forms:

  • Oral tablets: Typically available in 10 mg, 20 mg, 40 mg, 60 mg, and 80 mg
  • Extended-release capsules: Available in 60 mg, 80 mg, 120 mg, and 160 mg
  • Oral solution: Available in a concentration of 20 mg/5 mL and 40 mg/5 ml

Generic versions of propranolol are available.

Propranolol is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this medication.

Side Effects and Precautions for Propranolol


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What are the side effects of propranolol?

The use of propranolol can lead to various side effects in some individuals.

Common mild side effects of propranolol use include:

  • Dizziness
  • Tiredness
  • Nausea and vomiting
  • Diarrhea
  • Constipation
  • Insomnia or vivid dreams
  • Cold extremities

More severe side effects of propranolol use can include:

  • Allergic reactions (difficulty breathing, rash, hives, itching, swelling)
  • Faintness
  • Weight gain
  • Shortness of breath
  • Changes in heartbeat
  • Hallucinations

If you experience any severe or concerning side effects while taking propranolol, contact your healthcare provider right away.

What should I tell my healthcare provider before using propranolol?

Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with propranolol. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with propranolol.

Tell your provider if you are taking these medications or supplements:

  • Antacids that contain aluminum
  • NSAIDs
  • Blood pressure medications
  • Medications for heart rhythm
  • Warfarin
  • Antidepressants

You should also mention medical conditions such as:

  • Heart problems
  • Asthma
  • Kidney disease
  • Liver disease
  • Lung disease
  • Diabetes
  • Hyperthyroidism

If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using propranolol to assess potential risks and benefits.

Are there any other special instructions I should follow?

Take propranolol exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment.

Propranolol can affect your heart rate and blood pressure. Be aware of any symptoms of hypotension or bradycardia, such as dizziness, fainting, or unusually slow heartbeats.

Take propranolol at the same time every day to maintain an even level in your blood. For immediate-release formulations, it's often taken in divided doses. Extended-release capsules are usually taken once a day.

What should I do in case of an overdose?

In case of a propranolol overdose, seek medical attention immediately. Symptoms of overdose may include severe dizziness, fainting, difficulty breathing, or a very slow heart rate. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.

Proper Use & Dosage Information for Propranolol


Drug Information | Side Effects | Use & Dosage | Request an Online Prescription

What is the typical starting dose for propranolol?

Propranolol is available in the following forms:

  • Oral tablets (immediate-release and extended-release)
  • Oral solution (liquid)

The typical starting dose of propranolol varies depending on the condition being treated, the severity of symptoms, and individual patient factors. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.

For hypertension:

  • Adults: Typically, 80 mg of once daily (extended-release), which may be increased up to 120 mg to 160mg.
  • Children: Dosage is based on body weight and must be determined by your doctor.

For angina (chest pain):

  • Adults: Usually 80 mg once daily (extended-release).

For migraine prevention:

  • Adults: 80 mg once daily (extended-release).

The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history and your response to the medication.

Propranolol should be taken exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.

If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.

What should I do if I miss a dose of propranolol?

If you miss a dose of propranolol, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Take propranolol around the same time every day to ensure effectiveness.

What should I do if I'm feeling better while taking propranolol?

Continue taking propranolol as prescribed by your healthcare provider, even if you start feeling better. Do not stop the medication abruptly without consulting your provider, as it may lead to a return of symptoms or worsening of your condition.

If you have any concerns or questions about your medication, discuss them with your healthcare provider for medical advice and recommendations.

How should I store propranolol?

Store propranolol according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from light and moisture. Ensure the container is tightly closed and out of reach of children.

Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.

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