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Aripiprazole

Common Brand Names: Abilify

Drug Information

Medically reviewed by Jessica Swirble, PharmD
Last updated on April 18, 2025

Drug Information | Side Effects | Use & Dosage | Request an Online Prescription

Quick facts:

  • Brand Name: Abilify
  • Generic Name: Aripiprazole
  • Uses: Treatment for schizophrenia, bipolar disorder, major depressive disorder (as an adjunct with other forms of therapy), and irritability associated with autistic disorder
  • Drug Class: Atypical antipsychotic
  • Availability: Prescription only
  • Generic Status: Yes
  • Controlled Substance: No

What is aripiprazole?

Aripiprazole is a prescription medication used for the treatment of schizophrenia symptoms. It is also prescribed as a treatment for mental conditions such as bipolar disorder, major depressive disorder, and irritability symptoms in children with autistic disorder and Tourette’s syndrome.

What is aripiprazole used to treat?

Aripiprazole is prescribed as a treatment for symptoms caused by various mental disorders and conditions. Aripiprazole cannot cure conditions such as schizophrenia, bipolar disorder, or depression, but it can help patients manage them by reducing certain symptoms.

Aripiprazole is used to treat conditions such as:

  • Schizophrenia (in adults and children over 13)
  • Mania symptoms associated with bipolar disorder (in adults and children over 10)
  • Irritability symptoms associated with autistic disorder (in children between 6-17 years of age)
  • Symptoms of Tourette’s disorder (in children between 8-18 years of age)

What is aripiprazole used to treat?

Aripiprazole belongs to a classification of medications known as antipsychotic agents. Antipsychotics work by blocking certain dopamine receptors in the brain. By blocking these receptors, antipsychotics slow brain activity. This action can minimize psychotic symptoms caused by schizophrenia, depression, and bipolar disorder.

It’s important to note that aripiprazole is not a cure for schizophrenia, depression, autism, Tourette’s syndrome, or bipolar disorder. These are chronic conditions that require treatment over the course of a lifetime. Aripiprazole is prescribed to reduce symptoms of these disorders, making it easier to manage them.

How do I take aripiprazole?

Aripiprazole is available in the following forms:

  • Oral tablets
  • Orally disintegrating tablets (ODTs)
  • Oral solution (liquid)

The dosage and frequency of use depend on the condition being treated, its severity, and how you respond to the medication.

Follow your healthcare provider's instructions regarding dosage and schedule. Do not exceed the prescribed dose or frequency of use without consulting your provider.

How long until I feel better?

The time it takes to feel better can vary depending on the condition being treated and individual response to the medication. Some people may start noticing improvements within a few days, while for others, it might take several weeks.

Continue using aripiprazole as prescribed, even if you start feeling better. Regular use according to your prescription is crucial for managing your symptoms effectively.

Are there any other uses for aripiprazole?

While aripiprazole is primarily used for treating schizophrenia, bipolar disorder, major depressive disorder (along with other forms of therapy), and irritability associated with autism, healthcare providers may prescribe it off-label for other conditions such as anxiety or behavioral disorders.

Discuss any alternative uses of aripiprazole with your healthcare provider.

Dosage forms of aripiprazole

Aripiprazole is available in the following dosage forms:

  • Oral tablets
  • Orally disintegrating tablets (ODTs)
  • Oral solution (liquid)

Aripiprazole is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this medication.

Side Effects and Precautions for Aripiprazole


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What are the side effects of aripiprazole?

The use of aripiprazole can lead to various side effects in some individuals.

Common mild side effects of aripiprazole use include:

  • Headache
  • Anxiety/ Restlessness
  • Fatigue
  • Dizziness
  • Drowsiness
  • Heartburn
  • Stomach pain
  • Nausea
  • Weight gain
  • Constipation
  • Diarrhea
  • Vomiting
  • Changes in appetite
  • Insomnia
  • Joint pain

More severe side effects of aripiprazole use can include:

  • Symptoms of an allergic reaction (like skin rash, swelling, difficulty breathing or swallowing)
  • Seizures
  • Tremors or uncontrollable movements in the face, arms, or legs
  • Muscle stiffness, fever, sweating, confusion, or feeling faint
  • Fast or irregular heartbeat
  • Chills
  • Weakness
  • High cholesterol
  • Unusual bleeding or bruising
  • Increased thirst or increased urination
  • High blood sugar
  • Dry mouth

If you experience any severe or concerning side effects while taking aripiprazole, contact your healthcare provider right away.

What should I tell my healthcare provider before using aripiprazole?

Inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with aripiprazole. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with aripiprazole.

Tell your provider if you are taking these medications or supplements:

  • Allergy medications
  • Strong CYP3A4 Inhibitors (such as clarithromycin)
  • Strong CYP2D6 inhibitors (such as fluoxetine)
  • Strong CYP3A4 Inducers (such as carbamazepine)
  • Blood pressure medications
  • Benzodiazepines
  • Seizure medications
  • Pain medications
  • Medications for depression
  • Medications for sleep disorders

You should also mention medical conditions such as:

  • Heart disease
  • Heart failure
  • Heart attack
  • Irregular heartbeat
  • High or low blood pressure
  • Stroke
  • Ministroke
  • Seizures
  • Low white blood cell counts
  • High cholesterol
  • Balance problems
  • Conditions that make it difficult for you to swallow

If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using aripiprazole with your healthcare provider.

Are there any other special instructions I should follow?

Take aripiprazole exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or length of treatment.

Do not drive a car or operate machinery until you know how aripiprazole affects you.

Do not drink alcohol while using aripiprazole.

This medication can make you more sensitive to extreme temperatures. Talk to your provider if you plan to be in very hot or very cold temperatures. Drink plenty of water and other fluids while taking aripiprazole.

Aripiprazole can be taken with or without food. Taking it with food may help reduce stomach upset. It's important to follow your healthcare provider's instructions and complete the full course of treatment to effectively manage your condition.

What should I do in case of an overdose?

In case of an aripiprazole overdose, seek medical attention immediately. Symptoms of overdose may include severe drowsiness, rapid or unusual movements, dizziness, or fainting. If you suspect an overdose, contact the poison control helpline at 1-800-222-1222 or call emergency services.

Proper Use & Dosage Information for Aripiprazole


Drug Information | Side Effects | Use & Dosage | Request an Online Prescription

What is the typical starting dose for aripiprazole?

Aripiprazole is available in the following forms:

  • Oral tablets
  • Orally disintegrating tablets (ODTs)
  • Oral solution

The typical starting dose of aripiprazole varies depending on the condition being treated, the severity of symptoms, and the patient. It is crucial to follow your healthcare provider's instructions regarding dosage and administration.

For schizophrenia:

  • Adults: 10-15 mg (immediate-release) per day
  • Adolescents (13-17 years): 2 mg per day, which the doctor may increase gradually

For bipolar disorder:

  • Adults: 15 mg per day
  • Adolescents (10-17 years): 2 mg per day, which the doctor may increase gradually

For major depressive disorder (adjunctive therapy):

  • Adults: 2-5 mg per day

For irritability associated with autistic disorder:

  • Children (6-17 years): 2 mg per day, which may be adjusted gradually

The dosage may be adjusted based on the response and tolerance to the medication. Your healthcare provider will determine the most appropriate dose based on your medical history and your response to the medication.

Aripiprazole should be taken as prescribed by your healthcare provider. Do not exceed the recommended dose or duration of treatment without consulting your provider.

If you have any questions about your dosage or need adjustments, contact your healthcare provider for guidance. If you want to talk to a provider right away, consider scheduling an online doctor appointment through a telehealth platform like Sesame.

What should I do if I miss a dose of aripiprazole?

If you miss a dose of aripiprazole, take it as soon as you remember unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not double the dose to make up for a missed one.

Take aripiprazole around the same time every day to maintain an even level of medication in your body.

What should I do if I'm feeling better while taking aripiprazole?

Continue taking aripiprazole as prescribed by your healthcare provider, even if you start feeling better. It's important to keep taking the medication as directed to manage your condition effectively.

If you have any concerns or questions about your medication, discuss them with your healthcare provider for medical advice and recommendations.

How should I store aripiprazole?

Store aripiprazole according to the instructions provided by your healthcare provider or pharmacist. Keep it at room temperature, away from light and moisture. Ensure the container is tightly closed and out of reach of children.

Do not use expired medication or medications that appear damaged or discolored. If you have any questions about storage, consult your healthcare provider or pharmacist for guidance.

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