Yes, Rexulti is only available by prescription from a licensed provider.

Looking for a prescription? Sesame providers can prescribe Rexulti after an appointment. Simply schedule an online appointment with the provider of your choice. During the appointment, your provider will review your health history and current health needs to determine if Rexulti is appropriate for you. If Rexulti is recommended for you, it can be sent to the pharmacy of your choice.

Rexulti can cause both mild and serious side effects. Some side effects may be temporary as your body adjusts to the medication, while other side effects may occur after long-term treatment.

Common mild side effects include:

• Constipation
• Diarrhea
• Drowsiness
• Fatigue
• Headache
• Increased triglyceride levels
• Indigestion
• Insomnia
• Involuntary muscle spasms
• Tremors
• Uncontrollable need to move
• Weight gain

More severe side effects include:

• Allergic reactions
• Blood disorders
• Cardiovascular events (stroke, heart attack)
• Compulsive behavior
• High blood sugar
• Low blood pressure upon standing (orthostatic hypotension)
• Neuroleptic malignant syndrome
• Uncontrollable movement disorder (tardive dyskinesia)

Rexulti can also increase the risk of suicidal thoughts and behaviors, especially in children and young adults. Rexulti is only approved for children ages 13 and older with schizophrenia. Children and young adults should be monitored for changes in mood and behavior while taking Rexulti.

Rexulti can increase the risk of death in elderly patients with dementia-related psychosis. It is not approved for dementia-related psychosis without agitation.

Rexulti is classified as an atypical antipsychotic. It helps to treat both the positive and negative symptoms of schizophrenia. Positive symptoms include delusions, hallucinations, and disorganized thinking. Negative symptoms include social and emotional withdrawal and lack of motivation.

Examples of other atypical antipsychotics:

• Olanzapine (Zyprexa)
• Lurasidone (Latuda)
• Ziprasidone (Geodon)

It is also used in depression when antidepressants alone do not fully help. Rexulti can improve mood, energy, and motivation.

While they can be used for other mental health conditions, mood stabilizers are generally used for bipolar disorder. They help to regulate the mood and prevent episodes of mania and depression.