Misoprostol is used to prevent stomach ulcers in people who take NSAIDs long-term, such as for arthritis or chronic pain. Over-the-counter anti-inflammatories can weaken the stomach’s protective lining, increasing the risk of ulcers. Misoprostol helps reduce that risk by protecting the stomach from acid damage. It is not typically used to treat existing ulcers.

Depending on your condition and health history, your provider may recommend other prescription medications for gastrointestinal concerns. Sucralfate, esomeprazole, lansoprazole, rabeprazole, cimetidine, and hyoscyamine are all used to protect the stomach lining or manage acid-related symptoms.

Misoprostol starts working after your first few doses by strengthening the stomach’s protective lining. It may take several days to about a week to meaningfully reduce NSAID-related irritation.

This drug does not provide immediate symptom relief like an antacid. Instead, it works over time to help prevent ulcers from forming. For best protection, it should be taken consistently as prescribed while you are using NSAIDs.

Tell your healthcare provider about all medical conditions you have and all medications or supplements you take. There may be drug interactions with certain medications, including antacids containing magnesium.

Do not take misoprostol if you are pregnant or family planning, as it can cause serious complications. For this reason, your provider may ask if you are on birth control or have you take a pregnancy test before prescribing misoprostol. Contact your provider immediately if you become pregnant while taking this medication.

Misoprostol is not available over-the-counter. It requires a prescription from a licensed healthcare provider.

During a virtual or in-person visit on Sesame, a provider can evaluate your medical history and determine whether misoprostol is appropriate for you. If prescribed, your medication can be sent to a local pharmacy for pickup.

Misoprostol can only be obtained with a valid prescription from a licensed healthcare professional. Once prescribed, it is typically available at most retail pharmacies in its generic form or under the brand name as Cytotec pills.

Through Sesame, you can book an online appointment with a licensed provider who will assess your condition and treatment needs. If approved, your prescription can be sent to the pharmacy of your choice, often with same-day pickup available.

All prescriptions are issued at the discretion of the healthcare provider. Sesame does not guarantee that a prescription will be provided following an appointment.