Medically reviewed by Jessica Swirble, PharmD
Last updated on March 27, 2025
Drug Information | Side Effects | Use & Dosage | Request an Online Prescription
Molnupiravir is an antiviral medication used to treat COVID-19 infections in certain adult patients who have mild to moderate symptoms and are at high risk for severe illness.
Molnupiravir is prescribed as a treatment for mild to moderate coronavirus disease 2019 (COVID-19) infections in patients who may be at risk for developing a serious illness. It is only prescribed to patients who have received a positive test for COVID-19. This medication is not indicated for use as a prophylactic (preventative) against the disease. It is not a substitute for vaccination against COVID-19.
Molnupiravir belongs to a classification of medications known as antivirals. This medication works by inhibiting the ability of the SARS-CoV-2 virus to replicate. The more the virus can replicate, the more dangerous and infectious it becomes. By blocking this action, molnupiravir keeps the infection under control in the host body while reducing its infectiousness.
Molnupiravir is available as an oral tablet to be taken by mouth.
Molnupiravir starts working very quickly after you start taking it.
The time it takes to note the effects of molnupiravir will vary depending on the patient and the severity of the condition being treated. Most patients start feeling better within a few days after starting use. In the case of a severe infection, it may take longer before you feel better.
If you have been taking molnupiravir for several days and aren't feeling better, talk to your healthcare provider. Do not increase your dosage. If you are feeling better, do not stop using molnupiravir until your provider directs you to do so.
Providers will prescribe molnupiravir treatment for 5 days.
Molnupiravir is under emergency authorization for the treatment of COVID-19 in certain adult patients. It is not approved for use in other viral infections or conditions.
Molnupiravir is available as an oral capsule to be taken by mouth.
It is available under its generic name, molnupiravir.
Molnupiravir is only available via prescription. You must have a written prescription from a licensed healthcare provider to obtain this medication.
The use of molnupiravir has been shown to cause side effects in some patients.
Common mild side effects of molnupiravir use include:
More severe side effects include:
Seek medical attention immediately if you experience any severe symptoms while taking molnupiravir. If you experience mild side effects that become severe or do not go away after a few days, speak to a healthcare provider right away.
Tell your healthcare provider about any existing medical conditions, allergies, or other medications you are taking before starting treatment with molnupiravir. This includes prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with this drug.
Tell your provider if you are taking these medications or supplements:
You should also mention medical conditions such as:
Molnupiravir carries the risk of reproductive toxicity. Patients should use reliable birth control during treatment and for 4 days after the last dose of molnupiravir. Men should continue to use reliable contraception for 3 months after molnupiravir treatment.
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using molnupiravir to assess potential risks and benefits.
You can follow your regular diet while taking molnupiravir. Talk to your healthcare provider about the use of this drug with food, beverages, alcohol, and tobacco.
Your healthcare provider will tell you if you should avoid certain foods, beverages, or products while using molnupiravir. It is extremely important to follow their guidance, as certain drugs can interact with other substances in the body---leading to potentially severe reactions. If you have any questions about special instructions you should follow while taking this drug, talk to your healthcare provider before use.
If you suspect an overdose of molnupiravir or experience severe symptoms, seek immediate medical attention or contact the poison control helpline at 1-800-222-1222. Symptoms of an overdose may include worsening side effects or new symptoms not previously experienced.
If an individual has collapsed, is having seizures, or is unresponsive, call 9-1-1 immediately.
Molnupiravir is available in oral capsule form (200 mg).
The typical starting dose of molnupiravir for the treatment of COVID-19 varies depending on the specific protocol recommended by healthcare authorities or your healthcare provider. It is crucial to follow the prescribed dosage and treatment duration exactly as instructed.
For example, a common dosing regimen for molnupiravir in the treatment of COVID-19 might be:
However, dosing protocols may vary based on factors such as the severity of illness, patient age, weight, and other medical conditions. Always consult with your healthcare provider or follow the guidelines provided by health authorities for the most accurate and up-to-date information on dosing and administration.
It's important to take molnupiravir exactly as prescribed, even if you start feeling better before completing the full course of treatment. Do not adjust your dosage or stop taking the medication without consulting your healthcare provider.
If you have any questions about your dosage, contact your healthcare provider. If you want to talk to a provider right away, book an online doctor appointment on Sesame to discuss your concerns.
If you miss a dose, take it as soon as you remember it. If it's almost time for another dose of molnupiravir, skip the missed dose and take your next dose as scheduled. Do not take or apply a double dose of molnupiravir.
Do not discontinue or alter your molnupiravir dosage without consulting with your healthcare provider. Follow your healthcare provider's instructions regarding dosing and other recommendations for taking molnupiravir.
Store molnupiravir as directed by your healthcare provider or pharmacist. Proper storage is essential to maintain the medication's effectiveness. Molnupiravir should be stored at room temperature, away from excessive heat, light, and moisture.
Keep the medication out of the reach of children and ensure that the container is tightly closed.