Before starting treatment with phenelzine, inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking, including prescription drugs, over-the-counter medications, and dietary supplements, as they may interact with phenelzine.
Specifically, discuss any history of:
- Allergies to phenelzine or other MAOIs
- Hypertension (high blood pressure)
- Cardiovascular problems
- Liver disease
- Kidney disease
- Seizures
- Certain psychiatric conditions
- Asthma
- Pheochromocytoma
Avoid consuming foods and beverages that contain tyramine while taking phenelzine, as this can lead to a dangerous increase in blood pressure. Such foods and drinks include aged cheeses, cured meats, certain alcoholic beverages, and more.
You should also avoid foods or beverages containing phenylalanine, commonly found in products sweetened by aspartame.
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using phenelzine to assess potential risks and benefits.
Antidepressants like phenelzine can increase suicidal thoughts and actions. It is important to monitor signs and symptoms of worsening depression or changes in mood and behaviors.