Medically reviewed by Jessica Swirble, PharmD
Last updated on 4/2/2024

Drug Information | Side Effects | Use & Dosage| Request a Prescription

• Brand Name: Bactrim, Septra, Sulfatrim
  
• Generic Name: Sulfamethoxazole/Trimethoprim
  
• Uses: Bacterial infection treatment
  
• Drug Class: Combination antibiotic
  
• Availability: Prescription only
  
• Generic Status: Yes
  
• Controlled Substance: No
  
  

Sulfamethoxazole-trimethoprim is a combination antibiotic medication. It is commonly prescribed to treat bacterial infections such as urinary tract infections, respiratory tract infections, traveler's diarrhea, and certain types of pneumonia.

Sulfamethoxazole-trimethoprim is used to treat conditions such as:

• Urinary tract infections (UTIs)
  
• Respiratory tract infections
  
• Traveler's diarrhea
  
• Pneumonia (specific types)
  
  

It may also be prescribed for other bacterial infections as determined by your healthcare provider.

Sulfamethoxazole-trimethoprim works by inhibiting the production of folic acid in bacteria, which is essential for their growth and survival. By blocking this process, sulfamethoxazole-trimethoprim effectively kills or stops the growth of bacteria causing the infection.

Sulfamethoxazole-trimethoprim is typically taken orally, with a full glass of water, as directed by your healthcare provider.

You can take sulfamethoxazole-trimethoprim with or without food. Taking it with food may prevent stomach upset and irritation.

It is important to follow the prescribed dosage and schedule. Do not skip doses or stop taking sulfamethoxazole-trimethoprim before completing the full course, even if you feel better.

Consult your healthcare provider for specific instructions on how to take sulfamethoxazole-trimethoprim properly.

The time it takes to experience improvement in symptoms while taking sulfamethoxazole-trimethoprim can vary depending on the type and severity of the infection. Some people may start feeling better within a few days, while others may require the full course of treatment to see significant results. It's crucial to complete the prescribed course of sulfamethoxazole-trimethoprim as directed.

While sulfamethoxazole-trimethoprim is primarily used for bacterial infections, healthcare providers may sometimes prescribe it off-label for other conditions, such as:

• Acne (in certain cases)
  
• Toxoplasmosis
  
• Prevention of Pneumocystis jirovecii pneumonia (PCP) in certain populations
  
  

Discuss any alternative uses of sulfamethoxazole-trimethoprim with your healthcare provider.

Sulfamethoxazole-trimethoprim is available in its generic form (sulfamethoxazole-trimethoprim) in the following dosage forms:

• Oral tablets: Available in various strengths (e.g., sulfamethoxazole 400mg/trimethoprim 80mg or sulfamethoxazole 400mg/trimethoprim 160mg)
  
• Oral suspension: Available in different concentrations (e.g., sulfamethoxazole 200mg/trimethoprim 40mg per 5 mL)
  
  

The brand name sulfamethoxazole-trimethoprim has been discontinued. You can only get this medication in its generic form.

Sulfamethoxazole-trimethoprim is a prescription medication. You will need a valid prescription from a licensed healthcare provider to obtain this drug.