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Product Overview

Losartan-HCTZ (generic Hyzaar)

  • What is losartan/hydrochlorothiazide(HTCZ)?
    Losartan/HCTZ (generic Hyzaar) is a prescription medication used to treat high blood pressure (hypertension) and can help treat or prevent nephropathy (kidney disease or damage) in patients with type 2 diabetes and high blood pressure.

    Looking for a safe, effective way to keep your blood pressure under control? Talk to your doctor about whether losartan/HCTZ is right for you.

  • What are the most common side effects of losartan/htcz
    While adverse reactions to losartan/HCTZ are uncommon, some patients who take the drug may experience mild side effects, including muscle cramps or weakness; leg, knee, or back pain; diarrhea; heartburn; and decreased sensitivity to touch.

    Rare, more serious adverse events have also been known to occur. Contact your doctor if you are concerned that losartan/HCTZ may be causing you to experience any number of adverse side effects.

    Please note that this is not a complete list of side effects. For more information on adverse reactions you may experience while taking losartan/HCTZ, please visit the National Institutes of Health’s DailyMed webpage.

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Medically Reviewed By Dr. Allison Edwards, MD

Frequently asked questions about Losartan-HCTZ

Losartan/HCTZ (generic Hyzaar) is a combination of two prescription drugs - Losartan & hydrochlorothiazide - in a single form. Losartan/HCTZ is used to treat high blood pressure (hypertension). Losartan/HCTZ is also prescribed to reduce the risk of stroke in patients who have high blood pressure and in patients who have an enlarged heart.

High blood pressure is a common but serious disease. When not treated, it can lead to serious complications such as heart disease, heart attacks, kidney failure, loss of vision, strokes, and more. While medications such as Losartan are effective in helping lower blood pressure, doctors often prescribe these medicines alongside recommended lifestyle changes, like improving your diet, increasing your exercise, and abstaining from alcohol and tobacco.

Losartan/HCTZ is used to treat high blood pressure (hypertension), including in patients who are also dealing with an enlarged heart muscle (known as left ventricular hypertrophy).

Losartan/HCTZ may be prescribed for other uses. Talk to your doctor about whether Losartan/HCTZ is right for you.

Losartan is classified as a angiotensin II receptor antagonist. This class of drugs work by preventing blood vessels from tightening and constricting blood flow. Losartan relaxes and dilates your blood vessels, which lowers your blood pressure and increases the supply of blood and oxygen to your heart.

Hydrochlorothiazide belongs to a family of drugs known as thiazide diuretics, which are sometimes also known as “water pills.” These medicines work by stimulating your kidneys to get rid of your body’s excess salt and water via urine.

Dizziness or lightheadedness may occur as your body adjusts to this medication. Other common side effects include a cough, back pain, and upper respiratory infection (such as the common cold). Tell your doctor if any of these are severe or don’t go away.

Some side effects may be serious. Seek immediate medical attention if you experience any of the following:

  • Fainting
  • Decrease in vision or eye pain
  • Changes in your heartbeat
  • Increased/ decreased urine volume
  • Skin rash
  • Hives
  • Swelling of the face, lips, hands or feet

Be sure to tell your doctor if you are pregnant, breastfeeding, have a medical condition, or are taking any other medications.

Please note that this is not a complete list of all possible adverse reactions or precautions. For more information please visit the National Institutes of Health’s DailyMed webpage for losartan/HCTZ.

You may see some improvements to your blood pressure within the first week of using losartan/HCTZ. However, it may take 3 to 6 weeks for you to receive its full benefit.

You should continue to take losartan/HCTZ even if you feel well. High blood pressure often doesn’t have any noticeable symptoms. While this medication is effective at controlling your blood pressure, it does not cure it. Talk to your doctor if you want to discontinue using losartan/HCTZ.

The typical starting dose is 50 mg of losartan & 12/5 mg of hydrochlorothiazide taken once a day. The dosage may be increased after three weeks of therapy to a maximum of 100 mg losartan & 25 mg hydrochlorothiazide.

Please note that your dosage may be different depending on your age, the condition that you’re treating, and other factors. Take losartan/ HCTZ only as instructed by your doctor. Do not take more or less of it or take it more often than prescribed by your doctor.

Losartan/HCTZ is currently only available via prescription. This means the use of this drug must be authorized by a licensed health care provider.

Providers on Sesame can write a prescription – or refill an existing one – during a virtual or in-person visit. Depending on the medication, you can arrange for same-day pickup at a pharmacy near you. Book an online consultation with a real, licensed provider on Sesame today to determine whether or not losartan/HCTZ is right for you.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

Yes! Talk to a provider on Sesame and get your online doctor prescription or refill ordered right away for fast and convenient pickup from a pharmacy of your choice.

Note that all prescriptions are at the discretion of your clinician.

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