Avanafil (generic for Stendra) and Viagra are both prescription medications used to treat ED, but they contain different active ingredients. Stendra is the brand name for avanafil, while Viagra is the brand name for sildenafil.

Both medications belong to the same class of drugs, called PDE5 inhibitors, and work by increasing blood flow to the penis during sexual stimulation. Avanafil is often noted for its relatively fast onset of action. Sildenafil has been available longer.

Limit alcohol while taking avanafil, as it may increase side effects like dizziness or low blood pressure. Avoid taking avanafil with nitrates, such as nitroglycerin (Nitrostat) or isosorbide mononitrate, because combining them can cause a dangerous drop in blood pressure.

Avoid alpha blockers unless your provider specifically approves, as they may also lower blood pressure when combined with avanafil.

Certain medications, including some protease inhibitors (saquinavir, nelfinavir, indinavir, atazanavir, ritonavir), antifungals (itraconazole), and antidepressants (nefazodone), may interact with avanafil and increase side effects. Always check with your provider about any other meds you are taking.

Tell your provider about all supplements and medications you take, including alpha blockers, nitrates, antifungals, certain antibiotics (telithromycin), and antidepressants. Knowing your full medication list helps prevent dangerous interactions and ensures safe use of avanafil.

Combining medications like avanafil with other ED drugs like sildenafil, tadalafil, or vardenafil can significantly increase the risk of serious side effects.

Several other prescription medications are available to treat ED, depending on your needs and medical history. In addition to avanafil, commonly prescribed options include Sildenafil (generic for Viagra), Tadalafil (generic for Cialis), vardenafil, and Alprostadil (generic for Caverject Impulse, Edex).

Vardenafil, sildenafil, and tadalafil are oral medications in the same class as avanafil, called PDE5 inhibitors. Tadalafil is known for its longer duration of action. Alprostadil works differently. It increases blood flow directly and may be administered as a urethral suppository or penile injection.

Your healthcare provider can help determine which treatment option is safest and most effective for you based on your health history, preferences, and response to medication.

Avanafil is currently only available with a prescription. A licensed healthcare provider must evaluate you and determine whether this medication is safe and appropriate before authorizing its use.

If you’re seeking a prescription, Sesame providers can assess you during a virtual or in-person visit. They may write a new prescription or refill an existing one if clinically appropriate. Not all medications can be prescribed through a video visit, and in some cases, an in-person evaluation may be required.

All prescriptions are issued at the discretion of your healthcare provider, and approval is not guaranteed. Note that providers on Sesame are unable to prescribe controlled substances.

Yes, you can request an avanafil prescription online. If a Sesame provider determines that treatment is appropriate, they can send your prescription to a local pharmacy of your choice, often for same-day pickup.

All prescriptions are provided at the discretion of your healthcare provider following a medical evaluation.