Get a avanafil prescription online for ED

Get convenient and affordable avanafil prescriptions available for same-day pickup at your local pharmacy. Talk to a healthcare provider on Sesame to start treatment right away.

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Product Overview

Avanafil (generic for Stendra)

  • What is avanafil?
    Avanafil is a prescription medication used for the treatment of erectile dysfunction. It works by increasing blood flow and oxygen to the penis, making it easier to get and maintain an erection. Avanafil does not protect against the spread of sexually transmitted infections (STIs) or prevent pregnancy.

    Avanafil is available under the brand name Stendra. It can only be supplied via a prescription from a licensed health care provider.
    Talk to your health care provider about whether or not avanafil is right for you.

  • What are the common side effects of avanafil?
    Avanafil has been shown to cause some side effects. Talk to your health care provider if these adverse reactions do not go away within a few days.


Common side effects reported from avanafil use include:

  • Headache
  • Flushing
  • Muscle aches
  • Back pain

This is not a complete list of all possible side effects caused by avanafil.

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Medically Reviewed by Dr. Allison Edwards, MD

Frequently asked questions about avanafil

Avanafil is a prescription medication used for the treatment of erectile dysfunction. It works by increasing blood flow and oxygen to the penis, making it easier to get and maintain an erection. Though avanafil helps treat ED, it neither cures the condition nor increases sexual desire. Avanafil does not protect against the spread of sexually transmitted infections (STIs) or prevent pregnancy.

Avanafil is prescribed for the treatment of erectile dysfunction in men. Erectile dysfunction (ED) is a common condition in which you are unable to achieve and maintain an erection firm enough for sexual activity. In some cases, men who experience ED are unable to get an erection at all, while others are unable to get or maintain an erection firm enough for sex. Erectile dysfunction is one of the most common forms of male sexual dysfunction. In fact, ED affects nearly 30 million men worldwide.

Although many people will experience difficulties with their erections from time to time, if it is a frequent and ongoing issue, you should seek help from a medical professional. ED may also be a sign of an underlying health problem or a risk factor for heart disease.

Aside from age, common causes of ED include:

  • Poor vascular health (heart disease, high blood pressure, lack of blood flow)
  • Substance abuse
  • Diabetes
  • Obesity
  • Multiple sclerosis (MS)
  • Psychological problems (such as depression or anxiety)
  • Peyronie's disease (scar tissue inside the penis)
  • Spinal cord injuries
  • Medication usage

It is important to note that avanafil does not increase sex drive, nor is it a cure for the underlying causes of ED. It increases blood flow to the penis, which encourages an erection during sexual stimulation. It is also important to note that stimulation is required for avanafil to work. An erection cannot be attained, even after avanafil use, if the penis is not stimulated. Avanafil will not cause an erection on its own.

Avanafil will not protect against sexually-transmitted diseases or prevent pregnancy.

Avanafil belongs to a classification of medications known as phosphodiesterase 5 (PDE5) inhibitors. These medications work by preventing the breakdown of a naturally occurring biochemical in the body known as cyclic guanosine monophosphate (cGMP). Increased levels of cGMP improve the relaxation of blood vessels, making it easier to achieve and maintain an erection.

Even though avanafil increases blood flow to the penis, it cannot cause an erection by itself. Stimulation is required for the effects of avanafil to work.

Avanafil usage has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious effects, seek medical attention immediately.

Common side effects reported from avanafil use include:

  • Headache
  • Feeling of warmth (flushing)
  • Muscle aches
  • Back pain

More serious side effects include:

  • An erection that lasts more than 4 hours
  • Loss of vision
  • Dizziness
  • Ringing or pounding in the ears
  • Hearing loss
  • Rash
  • Itching
  • Swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a serious adverse reaction to this medication and require treatment right away.

As with all prescription medication, inform your doctor of any medical conditions you are currently managing. Tell them about any and all medication, prescription drugs, and supplements you are taking before starting treatment with avanafil. Avanafil can interact with substances in the body, causing potentially serious adverse reactions. Specifically, let your doctor know if you are currently taking any alpha-blockers, HIV protease inhibitors, or antifungal medication. In addition, let them know if you are currently taking any other form of erectile dysfunction medication.

Talk to your health care provider about safe drinking practices during treatment with avanafil. Avanafil can interact with alcohol and cause potentially serious adverse reactions like those listed above.

Take this medication exactly as prescribed by your health care provider. Keep all medication bottles out of reach of small children, and at room temperature. Avoid exposing the medication to excess heat or moisture. Seek medical attention right away if you begin to notice chest pain, trouble breathing, or signs of an allergic reaction (hives, rash, swelling) after taking the medicine.

Do not exceed the dosage prescribed, or discontinue the use of avanafil without consulting your health care provider first.

Avanafil is currently only available via prescription. This means that a licensed health care provider must authorize the use of this medication.

If you are looking for a prescription, doctors on Sesame can write a prescription–or refill an existing one–during a virtual or in-person visit. Note that not all drugs can be prescribed via an online video appointment. In some cases, an in-person doctor visit is required for a prescription.

Depending on the medication, you can arrange for same-day pickup at your pharmacy. Book an appointment with a provider on Sesame today to discuss whether or not avanafil is right for you.

Note that all prescriptions are at the discretion of your health care provider. Sesame cannot guarantee that you will be provided a prescription after a video or in-person appointment. Providers on Sesame are unable to prescribe controlled substances. For more information about controlled substances, check out the Drug Enforcement Agency’s scheduling guidelines here.

Good news! If deemed clinically appropriate, providers on Sesame can write a prescription for avanafil to be picked up near you – often within the same day! Simply talk to a clinician and get your online doctor prescription or refill ordered right away for fast and convenient pickup from a pharmacy of your choice.

Note that all prescriptions are at the discretion of your healthcare provider.

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