No, isosorbide is not available over the counter. It is only available by prescription from a licensed healthcare provider.

Do you have chest pain and need a refill or a new prescription? Make an appointment with a Sesame provider today so you can get relief from chest pain.

Isosorbide commonly causes side effects with use. Some side effects may go away as your body adjusts to the medication.

Side effects of isosorbide include:

• Headache
• Dizziness
• Fatigue
• Flushing
• Nausea
• Fainting
• Low blood pressure
• Low heart rate
• Increase in chest pain

Isosorbide mononitrate comes as an immediate-release tablet and an extended-release tablet. The brand names for the immediate-release tablet were Ismo and Monoket, but they have been discontinued.

The brand name for the extended-release tablet was Imdur, which has also been discontinued. Generic medications are available in both forms.

Isosorbide mononitrate is used to prevent chest pain (angina) caused by coronary artery disease.

Isosorbide mononitrate is a preventative medication and should not be used during an active attack. Nitroglycerin is often prescribed for sudden chest pain attacks.

Isosorbide dinitrate is also a nitrate and vasodilator used for preventing chest pain. It has a shorter duration of action and must be taken two to three times a day.

Isosorbide should not be used by anyone with an allergy to it, those with heart failure, or those who have had a recent heart attack.

Isosorbide mononitrate should also be avoided in people with the following conditions:

• Low blood pressure
• Recent head trauma
• Closed-angle glaucoma
• Hypertrophic cardiomyopathy

Speak with your healthcare provider if you are pregnant, planning on becoming pregnant, or breastfeeding.

You should not use medications for erectile dysfunction while taking isosorbide mononitrate. Medications such as sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra), and avanafil (Stendra) can cause an unsafe drop in blood pressure, which can lead to fainting, heart attacks, stroke, or death.

Riociguat, which is used for pulmonary hypertension, should also be avoided with isosorbide mononitrate. It can also cause an unsafe drop in blood pressure and fainting.

The price of isosorbide mononitrate ER will depend on whether you are paying cash or using insurance. The price with insurance for isosorbide will vary by plan and pharmacy.

The cost without insurance for isosorbide will vary depending on the pharmacy, location, quantity, and strength.

Looking to save money? Ask your provider about the Sesame Rx savings card, which can save you up to 80% off the price of your prescription.