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Yes! Semaglutide is available as an oral medication. The FDA has approved a pill form of semaglutide for weight loss called Wegovy pill.

For those with diabetes, the FDA has also approved an oral semaglutide pill to treat type 2 diabetes (Rybelsus). This gives people more flexibility in how they take their medication, no injections required.

Yes. Wegovy is now available as a once-daily pill for weight loss. It comes in 4 different dose strengths: 1.5 mg, 4 mg, 9 mg, and 25 mg.

If the Wegovy pill is appropriate for you, you can get a prescription through Sesame’s weight loss program, where a licensed healthcare provider evaluates your health history and goals before prescribing.

The main difference between the Wegovy pill and Wegovy injection is how they’re taken: the Wegovy pill is taken by mouth once daily on an empty stomach, while Wegovy injections come in the form of an injectable pen that is injected under the skin once a week.

In terms of effectiveness, the Wegovy pill and Wegovy injection are very similar. Clinical data show around 14% average weight loss with the Wegovy pill and nearly 15% average weight loss with Wegovy injections.

Side effects are also similar for both medications, and commonly include nausea, vomiting, diarrhea, and constipation. The injectable form of Wegovy can also cause injection-site reactions, such as redness or irritation, which do not occur with the pill.

Generally, yes. However, the Wegovy pill and injection result in nearly identical weight loss results, so switching from injections to the pill usually comes down to personal preference. For instance, if you don’t like needles or find pills easier to store or travel with, the oral semaglutide option might be a better fit.

The Wegovy pill is also more affordable than the Wegovy injection for self-pay patients. The monthly price for the maintenance dose of Wegovy pills (25 mg daily) is $299 per month, while the monthly price for the maintenance dose of Wegovy injections (2.4mg weekly) is $349 per month — a monthly savings of $50.

According to the FDA’s guidance, Wegovy pills may be a good option for adults aged 18 and up who:

• Have obesity, or overweight with weight-related medical conditions, and want help losing weight and keeping it off
• Have known heart disease and obesity or overweight, and are looking to reduce the risk of major cardiovascular events such as heart attack, stroke, or cardiovascular-related death

A licensed provider can help determine whether Wegovy is appropriate based on your full medical picture.

You can get Wegovy semaglutide pills through reputable online weight loss programs like Sesame’s Success by Sesame. You’ll meet virtually with a licensed healthcare provider who can prescribe an oral semaglutide medication like Wegovy for weight loss if it makes sense for you.

From there, your Sesame provider can help with monthly oral semaglutide refills and ongoing support (including guidance on nutrition, exercise, and sustainable habits) so you’re supported throughout your weight loss journey.