Nystatin is commonly prescribed as an oral tablet or suspension (liquid), vaginal application, or topical cream/ ointment.
Vaginal route: For vaginal yeast infections, one 100,000 unit application should be inserted into the vagina once or twice a day for two weeks. In some cases, one 500,000 unit application is prescribed to be inserted once a day for two weeks. Talk to your doctor about the proper way to fill the vaginal applicator and the correct way to insert the medication.
Oral route: For infections of the mouth, stomach lining, or intestines, nystatin is prescribed as an oral tablet, lozenge, or suspension (liquid). One to two lozenges or tablets should be taken three to five times a day for fourteen days. If taking the suspension medication, about 1 teaspoon should be taken four to six times a day. This dosage may vary for young children.
Topical route: For skin infections, apply topical nystatin cream or ointment to the affected area of the skin twice a day. Do not put a bandage or wrap over the infected skin.
Do not discontinue the use of nystatin unless instructed to do so by your doctor. Doing so can cause the fungal infection to recur. Additionally, do not increase your daily dosage of nystatin unless given a specific order by your doctor. Follow the full course of treatment and take the medication exactly as prescribed.