Prescription Medicine For Premature Ejaculation

About premature ejaculation

What is premature ejaculation?

Premature ejaculation (PE) is a common male sexual health condition in which you ejaculate sooner than you want to—often within one minute of penetration for lifelong PE or three minutes for acquired PE—along with an inability to delay ejaculation. This can lead to frustration and strained relationships. PE is often categorized into two groups:

Lifelong PE: This type of PE happens from your very first sexual experiences, where you consistently ejaculate within approximately one minute of penetration.
Acquired PE: This type develops at a later stage in life. With acquired PE, you usually ejaculate within three minutes or less.

For a clinical diagnosis, the lack of control and quick ejaculation must happen almost every time you have sex, not just once in a while.

What causes premature ejaculation?

The exact cause of PE is not yet fully understood. However, it usually stems from a mix of physical and mental factors. Depending on your type of PE, different underlying mechanisms may be involved:

Biological and neurobiological factors: Irregular levels of brain chemicals (like serotonin), genetic predispositions, hormonal imbalances, thyroid dysfunction, or inflammation/infection of the prostate or urethra
Psychological factors: Performance anxiety, relationship distress, depression, early sexual conditioning, or general life stress
Medical conditions: Cardiovascular disease, diabetes, high blood pressure, obesity, or substance abuse

Identifying the primary cause is an important step, since treatment plans are tailored to the root factor. You can book a video visit with a provider on Sesame to discuss your symptoms.

How to get virtual premature ejaculation treatment and medication through Sesame

Choose a provider

Browse real patient reviews and choose a men’s health expert who suits your needs to evaluate your symptoms during a confidential video visit.

Meet with your provider

Schedule your online consultation from the comfort of your own home and discuss your medical history, symptoms, and lifestyle. Your video visit will always be confidential.

Get your PE pill prescription

If appropriate, your provider will send your prescription directly to your local pharmacy, where you can pick up your medication. Follow up anytime to adjust your treatment plan if you need to.

Choose a provider

Browse real patient reviews and choose a men’s health expert who suits your needs to evaluate your symptoms during a confidential video visit.

Meet with your provider

Schedule your online consultation from the comfort of your own home and discuss your medical history, symptoms, and lifestyle. Your video visit will always be confidential.

Get your PE pill prescription

If appropriate, your provider will send your prescription directly to your local pharmacy, where you can pick up your medication. Follow up anytime to adjust your treatment plan if you need to.

Let's get started

Why do I need a prescription for premature ejaculation treatment?

Prescription PE medications like SSRIs or PDE5 inhibitors affect your nervous and cardiovascular systems. A provider can choose the appropriate dosage, screen for drug interactions, and confirm the treatment is safe for your health history.

Is premature ejaculation medication effective?

Yes, clinical studies show that daily or on-demand SSRIs and topical anesthetics delay ejaculation and improve sexual satisfaction for most men with premature ejaculation. The FDA has not specifically approved any pills for premature ejaculation. However, several prescription medications are widely and safely used off-label to treat it.

Can masturbation help delay ejaculation?

Yes, masturbating 1 to 2 hours before sexual activity can lower sensitivity and reduce anxiety. This can build ejaculatory control over time, especially when combined with behavioral methods.

Why is ED medication sometimes prescribed for premature ejaculation?

ED and PE often occur together. ED medications can help maintain a firm erection. This can reduce performance anxiety and give you greater control over the timing of ejaculation.

Will PE medication automatically give me an erection?

No, medications like SSRIs or topical anesthetics delay ejaculation and decrease sensitivity. They do not affect erections. Even PDE5 inhibitors require sexual arousal to trigger an erection.

How is sertraline used to treat premature ejaculation?

Sertraline is one of the most common medications prescribed for PE. It changes serotonin levels in the central nervous system, delaying the ejaculatory reflex. It can be taken daily or when needed a few hours before sexual activity, as advised by a healthcare provider.

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