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Get semaglutide online prescriptions for weight loss or type 2 diabetes

Book with a top-rated provider of your choice through Sesame's weight loss program to see if semaglutide GLP-1 medication is right for you.

The cost of medications is not included in the price of this subscription.

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  • Semaglutide prescriptions available, if appropriate
  • Prescription pickup available at a pharmacy near you
  • Insurance coordination for medication coverage
  • 4.5 on Trustpilot
Sesame’s weight loss program is a month-to-month subscription for individuals who are looking to lose or manage their weight. It includes:
  • Medical history review and lifestyle assessment
  • Initial video consult
  • Ongoing care for weight loss and management
  • Unlimited messaging with provider
  • Prescription, if recommended
  • Order for lab(s) relevant to weight loss treatment/diagnoses (excludes NJ, NY, and RI)
  • Cost of lab(s) relevant to weight loss treatment/diagnoses (excludes NJ, NY, and RI)
  • Insurance coordination for prescription authorization
Not included in this subscription:
  • Cost of medication
  • Controlled substance prescription

Interested in weight loss? Learn about Sesame’s program.

Choose your own provider

Find the right fit by selecting a board-certified Sesame provider who speaks to you.

Medications made easy

Medication delivered straight to your door or preferred pharmacy.

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Close clinical supervision focused on sustainable, long-term changes to:

Exploring weight loss options? Sesame can help - with or without insurance.

Pick a Sesame provider who’s right for you.

Here's how Success by Sesame works:

1
Tell us about your weight loss history & goals

Answer a few questions to help us personalize your weight loss program, then choose your Sesame provider.

2
Meet with your Sesame provider

Talk to your provider about your medical history and weight loss goals in a video consult. They'll tailor a treatment plan and order a lab test if metabolic data is needed.

3
Begin treatment

Your provider will prescribe a weight loss medication that's right for you (if appropriate). Sesame will send the medication to your door or preferred pharmacy.

4
Ongoing support

Achieve your weight loss goals with unlimited messaging with your chosen provider and follow up visits as needed to monitor progress and adjust treatment.

Let's get started
Product Overview

Semaglutide

What is semaglutide?
Semaglutide is an active ingredient in several different brands of prescription drugs that have been FDA-approved for weight loss or type 2 diabetes.

Wegovy, a brand-name drug, is FDA-approved to treat weight loss in patients with obesity and overweight. Wegovy is prescribed in conjunction with other treatment measures such as exercise and dietary changes to help patients lose weight and prevent serious weight-related health issues.

Ozempic and Rybelsus are brand-name drugs FDA-approved to treat type 2 diabetes. While they use the same active ingredient as Wegovy, the FDA has not approved them for weight loss.

Talk to a healthcare provider to see if semaglutide is right for you. Note that because Ozempic and Rybelsus are not FDA-approved for weight loss it is unlikely that insurance will cover the drug for weight loss. Wegovy is the only semaglutide injection medication approved for weight loss.

What are the most common side effects of semaglutide?
Semaglutide has been shown to cause some mild side effects. If these adverse effects do not go away within a few days, talk to your health care provider.


Common side effects include:

  • Nausea
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Vomiting
  • Constipation

This is not a complete list of possible adverse effects.

Your provider will help you stay on track.

In 3 monthsMaterial Arrow Forward Icon
Lose 5%of your body weight
In 6 monthsMaterial Arrow Forward Icon
Lose 10%of your body weight
In 12 monthsMaterial Arrow Forward Icon
Lose 15%of your body weight

Results may vary. Milestones are based on semaglutide clinical trial averages.

See how much weight you can lose

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Frequently asked questions about semaglutide

Medically reviewed by:Allison Edwards, MD

Semaglutide is the active ingredient in the brand-name medications Wegovy, Ozempic and Rybelsus.

Wegovy is FDA-approved for weight loss in patients with obesity or who are overweight with other comorbidities such as high blood pressure, PCOS or obstructive sleep apnea.

Ozempic and Rybelsus are FDA-approved to treat type 2 diabetes.

Ozempic and Rybelsus are not FDA-approved for weight loss. Their use to help with weight loss is off-label, meaning that weight loss is not the primary use of either of these drugs. Insurance providers generally do not offer coverage for the off-label use of prescription drugs.

Semaglutide is the active ingredient in the brand name medications Ozempic, Rybelsus, and Wegovy.

Ozempic and Rybelsus are FDA-approved to treat type 2 diabetes.

Wegovy is FDA-approved for weight loss in patients with obesity or who are overweight with other comorbidities such as high blood pressure, PCOS or obstructive sleep apnea.

Ozempic and Rybelsus are not FDA-approved to promote weight loss. The use of Ozempic and Rybelsus to help with weight loss is strictly off-label, meaning that weight loss is not the primary use of either of these drugs.

Semaglutide is classified as an incretin mimetic, a category of anti-diabetes medication that acts like incretin hormones (hormones released by the pancreas to stimulate a decrease in blood glucose levels). Semaglutide binds to incretin receptors and prompts your pancreas to produce more insulin. The insulin then helps your body to break down and metabolize glucose in your blood, which keeps your blood sugar levels in check.

Semaglutide use has been shown to cause some mild side effects. If these adverse effects do not go away within a few days, talk to your health care provider.

Common side effects include:

  • Nausea
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Vomiting
  • Constipation

This is not a complete list of possible adverse effects.

If you experience an unexplained rash, swelling, stomach pain, difficulty breathing, decreased urination, changes in vision, or itchy skin while taking semaglutide, seek medical attention immediately. These are early signs of a potentially serious adverse reaction to the medication reaction.

Talk to your healthcare provider about any medication you are currently taking, or any medical conditions you have been previously diagnosed with before starting treatment with semaglutide.

Semaglutide is commonly administered as an injection. An initial subcutaneous (under the skin) injection of semaglutide is typically administered once a week for 4 weeks. Your provider may adjust or increase your dosage every 4 weeks – usually not exceeding more than 2.4 mg per week. These injections should be administered under the skin of the stomach, thigh, or upper arm. Use a different part of the body each time you apply an injection.

Semaglutide is available in pill form under the brand name Rybelsus. Rybelsus is used to treat type 2 diabetes. The initial dose of Rybelsus will depend on the instructions of your healthcare provider.

Do not discontinue or increase your dosage of semaglutide without consulting your healthcare provider first. Take the medication exactly as prescribed, and inform your healthcare provider if you begin to experience any side effects while taking the medication.

Semaglutide is currently only available via prescription. This means the use of this drug must be authorized by a licensed health care provider.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

Providers on Sesame can write a prescription for semaglutide to be picked up near you – often within the same day. Don’t wait to get your prescription filled. Talk to a provider on Sesame and get your prescription ordered right away for fast and convenient pickup from a pharmacy of your choice.

Sesame does not guarantee insurance coverage for medication. If you are uninsured, please be aware that GLP-1 medications like Ozempic, Wegovy and Rybelsus can be expensive, typically ranging between $950 to $1,600 per month. If you are insured, your provider can assist with insurance pre-authorization paperwork to cover the cost of your medication.

No, there are currently no generic alternatives to semaglutide. Although there are other semaglutide medications (Wegovy, Ozempic, Rybelsus) on the market, all GLP-1 agonist drugs are available only as brand-name products.

If you need assistance with navigating your options, you can schedule a online video consult with a provider through Success by Sesame, Sesame's weight loss program, to discuss the best medication for your needs.

Compounded semaglutide is a customized pharmaceutical formulation of the medication semaglutide that is prepared by a compounding pharmacy. The federal government allows providers to prescribe compounded versions of medication during drug shortages.

Compounded semaglutide can be prescribed online and through telehealth. Here at Sesame, these prescriptions are entirely at the discretion of the healthcare provider.

Sesame's weight loss program subscription pricing starts at just $89 per month for patients who do not require medication or will purchase their own medication from their preferred pharmacy. This is a good option for eligible Sesame patients who have insurance coverage for name-brand GLP-1 medications, such as Wegovy, Zepbound or Saxenda.

It's important to note that brand-name GLP-1 medications like Wegovy, Zepbound or Saxenda can be expensive without insurance coverage, typically ranging between $950 to $1,600 per month out-of-pocket. If you are insured, your provider can assist with insurance pre-authorization paperwork to help reduce the cost of your medication.

Sesame also offers a weight loss program subscription that includes medication for just $249 per month. This option includes the price of pre-measured, high-quality injectable compounded semaglutide at cost for those who are prescribed it, along with free home delivery.

Note that providers on Sesame set their own prices, which means that some providers may offer the service at a higher price.

Certain GLP-1 therapies such as semaglutide (the active ingredient in Ozempic, Rybelsus, and Wegovy), liraglutide (the active ingredient in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound) may increase the likelihood of developing thyroid gland tumors, including MTC, a type of thyroid cancer. This conclusion is based on studies where laboratory animals given semaglutide, liraglutide, tirzepatide and other GLP-1 medications developed tumors. However, it is not yet confirmed if these medications pose the same risk to humans. You can find additional information about the risks of FDA-approved medications that contain semaglutide here.

It’s important to inform your doctor if you or any family member has ever had MTC or MEN. If this is the case, your doctor will likely advise against taking GLP-1 medications.

If you are prescribed a GLP-1 medication and exhibit any of the following symptoms, you should contact your provider immediately:

  • A lump or swelling in the neck
  • Hoarseness
  • Difficulty swallowing
  • Shortness of breath
  • Severe abdominal pain

Before taking GLP-1 medications, you should also discuss the following with your provider:

Allergies: Inform your doctor and pharmacist of any allergies you have to semaglutide (including under brand names Ozempic, Rybelsus, Wegovy) or similar medications such as tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon BCise, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy) and lixisenatide (Adlyxin, or in Soliqua).

Personal and family medical history: Be sure to disclose if you have a history of medical conditions like pancreatitis, diabetic retinopathy, gallbladder disease or kidney disease. Inform your doctor about recent episodes of diarrhea, nausea, vomiting or any inability to consume liquids, which could lead to dehydration.

Current medications and supplements: Provide a comprehensive list of all medicines and supplements you are currently taking, including prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products. This is crucial as GLP-1 medications can alter how your body absorbs oral medications.

Pregnancy and breastfeeding: Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon.

Surgical procedures: In the event of surgery, including dental procedures, inform the medical or dental professional that you are on GLP-1 medication.

It's essential to thoroughly discuss these risks with your healthcare provider and consider your personal and family medical history when deciding whether to use these medications. Your doctor can provide guidance on the best course of action based on your specific health situation.

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