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Get semaglutide online prescriptions for weight loss or type 2 diabetes

Book with a top-rated provider through Sesame's weight loss program to see if semaglutide GLP-1 medication is right for you.

The cost of medications is not included in the price of this subscription.

  • Doctor
    Semaglutide prescriptions available, if appropriate
  • Pill
    Prescription pickup available at a pharmacy near you
  • Chat
    Insurance coordination for medication coverage
  • 4.3 on Trustpilot
Sesame’s weight loss program is a 3-month subscription which includes:
  • A video consultation with your chosen provider
  • Semaglutide prescription + refills, if clinically appropriate
  • Insurance coordination for prescription authorization
  • Ongoing support via unlimited messaging, nutrition, and exercise guidance
  • Lab order (if needed)
Not included in this subscription:
  • Cost of medication
  • Cost of lab work (if needed)

Book a visit to get started

Choose from top-rated clinicians to kick off your weight loss journey with a video consultation & unlimited messaging.
Product Overview

Semaglutide

What is semaglutide?
Semaglutide is an active ingredient in several different brands of prescription drugs that have been FDA-approved for weight loss or type 2 diabetes.

Wegovy, a brand-name drug, is FDA-approved to treat weight loss in patients with obesity and overweight. Wegovy is prescribed in conjunction with other treatment measures such as exercise and dietary changes to help patients lose weight and prevent serious weight-related health issues.

Ozempic and Rybelsus are brand-name drugs FDA-approved to treat type 2 diabetes. While they use the same active ingredient as Wegovy, the FDA has not approved them for weight loss.

Talk to a healthcare provider to see if semaglutide is right for you. Note that because Ozempic and Rybelsus are not FDA-approved for weight loss it is unlikely that insurance will cover the drug for weight loss. Wegovy is the only semaglutide injection medication approved for weight loss.

What are the most common side effects of semaglutide?
Semaglutide has been shown to cause some mild side effects. If these adverse effects do not go away within a few days, talk to your health care provider.


Common side effects include:

  • Nausea
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Vomiting
  • Constipation

This is not a complete list of possible adverse effects.

Providers you can trust. Results you can see.

Billed every three months to match your personalized journey.
3 months
Lose up to 5% of your body weight
Start treatment and access close monitoring and support to help you meet your goals.
6 months
Lose up to 10% of your body weight
Track progress with your provider via ongoing care and unlimited messaging. Adjust treatment if needed.
12 months
Lose up to 15% of your body weight
Stay on track and celebrate your success! Connect with your provider to plan how to maintain a healthy weight.

How it works

Get started

Select your provider

Choose a qualified healthcare professional with in weight management.

As soon as today

Meet with your provider

Talk to your provider about your history, weight goals and treatment plan; they’ll order a lab test if you lack recent metabolic data.

Immediately after your appointment

Provider sends Rx (if appropriate)

If medication is prescribed, your provider will handle insurance paperwork and send the prescription to your pharmacy.

Varies by pharmacy

Start treatment

Begin your prescribed weight loss program with the medication or therapy provided.

Ongoing care

Provider support


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Frequently asked questions about semaglutide

Medically reviewed by:
Allison Edwards, MD

Semaglutide is the active ingredient in the brand-name medications Wegovy, Ozempic and Rybelsus.

Wegovy is FDA-approved for weight loss in patients with obesity or who are overweight with other comorbidities such as high blood pressure, PCOS or obstructive sleep apnea.

Ozempic and Rybelsus are FDA-approved to treat type 2 diabetes.

Ozempic and Rybelsus are not FDA-approved for weight loss. Their use to help with weight loss is off-label, meaning that weight loss is not the primary use of either of these drugs. Insurance providers generally do not offer coverage for the off-label use of prescription drugs.

Semaglutide is the active ingredient in the brand name medications Ozempic, Rybelsus, and Wegovy.

Ozempic and Rybelsus are FDA-approved to treat type 2 diabetes.

Wegovy is FDA-approved for weight loss in patients with obesity or who are overweight with other comorbidities such as high blood pressure, PCOS or obstructive sleep apnea.

Ozempic and Rybelsus are not FDA-approved to promote weight loss. The use of Ozempic and Rybelsus to help with weight loss is strictly off-label, meaning that weight loss is not the primary use of either of these drugs.

Semaglutide is classified as an incretin mimetic, a category of anti-diabetes medication that acts like incretin hormones (hormones released by the pancreas to stimulate a decrease in blood glucose levels). Semaglutide binds to incretin receptors and prompts your pancreas to produce more insulin. The insulin then helps your body to break down and metabolize glucose in your blood, which keeps your blood sugar levels in check.

Semaglutide use has been shown to cause some mild side effects. If these adverse effects do not go away within a few days, talk to your health care provider.

Common side effects include:

  • Nausea
  • Stomach pain
  • Diarrhea
  • Loss of appetite
  • Vomiting
  • Constipation

This is not a complete list of possible adverse effects.

If you experience an unexplained rash, swelling, stomach pain, difficulty breathing, decreased urination, changes in vision, or itchy skin while taking semaglutide, seek medical attention immediately. These are early signs of a potentially serious adverse reaction to the medication reaction.

Talk to your healthcare provider about any medication you are currently taking, or any medical conditions you have been previously diagnosed with before starting treatment with semaglutide.

Semaglutide is commonly administered as an injection. An initial subcutaneous (under the skin) injection of semaglutide is typically administered once a week for 4 weeks. Your provider may adjust or increase your dosage every 4 weeks – usually not exceeding more than 2.4 mg per week. These injections should be administered under the skin of the stomach, thigh, or upper arm. Use a different part of the body each time you apply an injection.

Semaglutide is available in pill form under the brand name Rybelsus. Rybelsus is used to treat type 2 diabetes. The initial dose of Rybelsus will depend on the instructions of your healthcare provider.

Do not discontinue or increase your dosage of semaglutide without consulting your healthcare provider first. Take the medication exactly as prescribed, and inform your healthcare provider if you begin to experience any side effects while taking the medication.

Semaglutide is currently only available via prescription. This means the use of this drug must be authorized by a licensed health care provider.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

Providers on Sesame can write a prescription for semaglutide to be picked up near you – often within the same day. Don’t wait to get your prescription filled. Talk to a provider on Sesame and get your prescription ordered right away for fast and convenient pickup from a pharmacy of your choice.

Sesame does not guarantee insurance coverage for medication. If you are uninsured, please be aware that GLP-1 medications like Ozempic, Wegovy and Rybelsus can be expensive, typically ranging between $950 to $1,600 per month. If you are insured, your provider can assist with insurance pre-authorization paperwork to cover the cost of your medication.

No, there are currently no generic alternatives to semaglutide. Although there are other semaglutide medications (Wegovy, Ozempic, Rybelsus) on the market, all GLP-1 agonist drugs are available only as brand-name products.

If you need assistance with navigating your options, you can schedule a video consult with a provider through Sesame’s weight loss program to discuss the best medication for your needs.

Sesame’s online weight loss program is a subscription that renews every 3 months and includes a video consultation with a weight loss provider, a prescription for semaglutide, liraglutide, tirzepatide, or other weight loss medication if deemed clinically appropriate, assistance with pre-authorization for medication coverage, and 90 days of unlimited messaging with your provider.

Sesame does not accept insurance in order to keep prices low and transparent, which means that the cost of the weight program will not be covered by insurance. It's important to note that the cost of medication is not included in this program, and Sesame does not guarantee medication pricing or insurance coverage for medication.

In addition, most insurance companies will not cover the off-label use of prescription drugs. __That means you will likely not be able to get insurance coverage if you are prescribed:

  • Ozempic
  • Rybelsus
  • Mounjaro
  • Victoza

If you are uninsured, please be aware that GLP-1 medications like Wegovy can be expensive, typically ranging between $950 to $1,600 per month. If you are insured, your provider can assist with insurance pre-authorization paperwork to cover the cost of your medication.

Your provider may order a metabolic panel if you do not have recent metabolic testing data available. If this is the case, the price of your lab test is not included in the program cost.

Certain GLP-1 therapies such as semaglutide (the active ingredient in Ozempic and Wegovy), liraglutide (the active ingredient in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound) may increase the likelihood of developing thyroid gland tumors, including medullary thyroid carcinoma (MTC), a type of thyroid cancer. This conclusion is based on studies where laboratory animals given semaglutide, liraglutide and tirzepatide developed tumors. However, it is not yet confirmed whether semaglutide, liraglutide and tirzepatide pose the same risk to humans.

It’s important to inform your doctor if you or any family member has ever had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), a condition leading to tumors in multiple glands. If this is the case, your doctor will likely advise against taking GLP-1 medications such as semaglutide, tirzepatide or liraglutide.

If you are prescribed a GLP-1 medication such as Ozempic, Wegovy, Mounjaro or Saxenda and exhibit any of the following symptoms, you should contact your provider immediately:

  • A lump or swelling in the neck
  • Hoarseness
  • Difficulty swallowing
  • Shortness of breath

Before taking GLP-1 medications, you should also discuss the following with your provider:

  • Allergies: Inform your doctor and pharmacist of any allergies you have to semaglutide (including under brand names Ozempic, Rybelsus, Wegovy) or similar medications such as tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy), and lixisenatide (Adlyxin, or in Soliqua).
  • Personal and family medical history: Be sure to disclose if you have a history of conditions like pancreatitis, diabetic retinopathy, gallbladder disease, or kidney disease. Inform your doctor about recent episodes of diarrhea, nausea, or vomiting, or any inability to consume liquids, which could lead to dehydration.
  • Current Medications and Supplements: Provide a comprehensive list of all medicines and supplements you are currently taking, including prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products. This is crucial as GLP-1 medications can alter how your body absorbs oral medications.
  • Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon.
  • Surgical procedures: In the event of surgery, including dental procedures, inform the medical or dental professional that you are on GLP-1 medication.

It's essential to thoroughly discuss these risks with your healthcare provider and consider your personal and family medical history when deciding whether to use these medications. Your doctor can provide guidance on the best course of action based on your specific health situation.

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