Get semaglutide online prescriptions for weight loss or type 2 diabetes

You can get a semaglutide prescription online through Sesame for brand names like Ozempic, Wegovy, and Rybelsus if it's deemed clinically appropriate by one of our medical providers.

Sesame offers two ways to get evaluated for a semaglutide prescription:

• Success by Sesame (for weight loss): You’ll meet with a dedicated provider who can evaluate you and, if medically appropriate, prescribe GLP-1s like Wegovy for weight loss.
• EverydayRx (for diabetes): You meet with a dedicated provider who can assess your needs and prescribe GLP-1 diabetes medications like Ozempic or Rybelsus.

You can get semaglutide for weight loss online through a telehealth weight loss program like Success by Sesame.

After an easy online visit, your Sesame provider can determine if it’s appropriate for you. If it is, they can write a prescription for semaglutide or another weight loss medication, help with monthly Rx refills, and provide ongoing support with nutrition, sleep, and healthy habits throughout your journey.

Other weight loss medications that can be prescribed through Success by Sesame include:

• Zepbound (tirzepatide)
• Saxenda (liraglutide)
• Contrave (bupropion naltrexone)

The difference between semaglutide and compounded semaglutide is that semaglutide is an FDA-approved prescription medicine made by a drug manufacturer (for example, Ozempic, Wegovy, or Rybelsus). It’s produced under strict quality standards, comes in a standardized dose and delivery method, and is dispensed by regular pharmacies.

Compounded semaglutide is a custom-made version prepared by a compounding pharmacy, sometimes in different forms or concentrations. Because compounded semaglutide isn’t the same as the FDA-approved product, the strength, ingredients, and quality controls can vary by pharmacy, and it may not be reviewed the same way as brand-name products.

Compounded semaglutide is not currently available through Sesame. However, your Sesame provider can discuss alternative GLP-1 medications with you.

For oral semaglutide (Wegovy pill, Rybelsus), it should typically be taken once daily on an empty stomach, ideally at the same time each day. Tablets should be stored in a cool, dry place away from direct sunlight.

For injectable semaglutide (Wegovy pen, Ozempic), the medication should be injected once weekly under the skin of the stomach, thigh, or upper arm. Use a different part of the body each time you apply an injection. Injectable semaglutide must be kept refrigerated at 36–46°F (2–8°C).

It varies depending on the form (pill or injection), the condition you’re taking semaglutide for, and the type of semaglutide medication you're taking (Ozempic, Wegovy or Rybelsus). Here’s what typical starting doses look like for each semaglutide medication:

• Ozempic (weekly injection, for type 2 diabetes): often starts at 0.25 mg once weekly for 4 weeks, then your dose is usually increased.
• Wegovy pen (weekly injection, for weight loss): often starts at 0.25 mg once weekly for 4 weeks, then is gradually increased over time.
• Wegovy pill (daily pill, for weight loss): often starts at 1.5 mg once a day for 4 weeks, then is gradually increased over time.
• Rybelsus (daily pill, for type 2 diabetes): often starts at 3 mg by mouth once daily for 30 days, then is increased.

It’s important to note that your starting dose can vary based on your health history, other medications, side effects, and goals. Follow your medical provider’s instructions and ask them what’s right for you.

No, there are currently no generic alternatives to semaglutide. Although there are several semaglutide medications (Wegovy, Ozempic, Rybelsus) on the market, these are available only as brand-name products.

Need assistance with navigating your options? For weight loss, schedule an online video consult with a provider through Success by Sesame, Sesame's weight loss program, to discuss your options and get an Rx if appropriate.

For diabetes, schedule an online video consult with a provider through Everyday Rx, Sesame’s prescription refill program, to discuss your options and get an Rx if appropriate.

Certain GLP-1 therapies such as semaglutide (the active ingredient in Ozempic, Rybelsus, and Wegovy), liraglutide (the active ingredient in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound) may increase the likelihood of developing thyroid gland tumors, including MTC, a type of thyroid cancer. This conclusion is based on studies where laboratory animals given semaglutide, liraglutide, tirzepatide and other GLP-1 medications developed tumors. However, it is not yet confirmed if these medications pose the same risk to humans. You can find additional information about the risks of FDA-approved medications that contain semaglutide here.

It’s important to inform your doctor if you or any family member has ever had MTC or MEN. If this is the case, your doctor will likely advise against taking GLP-1 medications.

If you are prescribed a GLP-1 medication and exhibit any of the following symptoms, you should contact your provider immediately:

• A lump or swelling in the neck
  
• Hoarseness
  
• Difficulty swallowing
  
• Shortness of breath
  
• Severe abdominal pain

Before taking GLP-1 medications, you should also discuss the following with your provider:

Allergies: Inform your doctor and pharmacist of any allergies you have to semaglutide (including under brand names Ozempic, Rybelsus, Wegovy) or similar medications such as tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon BCise, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy) and lixisenatide (Adlyxin, or in Soliqua).

Personal and family medical history: Be sure to disclose if you have a history of medical conditions like pancreatitis, diabetic retinopathy, gallbladder disease or kidney disease. Inform your doctor about recent episodes of diarrhea, nausea, vomiting or any inability to consume liquids, which could lead to dehydration.

Current medications and supplements: Provide a comprehensive list of all medicines and supplements you are currently taking, including prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products. This is crucial as GLP-1 medications can alter how your body absorbs oral medications.

Pregnancy and breastfeeding: Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon.

Surgical procedures: In the event of surgery, including dental procedures, inform the medical or dental professional that you are on GLP-1 medication.

It's essential to thoroughly discuss these risks with your healthcare provider and consider your personal and family medical history when deciding whether to use these medications. Your doctor can provide guidance on the best course of action based on your specific health situation.

If you don’t have insurance coverage, the Wegovy pill is cheaper than alternatives like Ozempic, Wegovy pens, and Rybelsus. It’s currently priced at $149 per month for 1.5 mg and 4 mg doses (usually taken during your first few months of treatment) and $299 per month for 9 mg and 25 mg doses (the standard maintenance doses.)

Here’s what semaglutide prices look like, ranked from least expensive to most expensive:

• Wegovy pill: $149/mo. for lower doses (1.5mg, 4mg) or $299/mo for higher doses (9 mg, 25 mg)
• Wegovy pen: $199/mo. for first two months (new Wegovy patients only), then $349/mo after
• Ozempic pen: $199/mo. for first two months (new Ozempic patients only), then $349/mo after
• Rybelsus pill: Around $1,000/month (depending on your pharmacy)

If you have insurance coverage, you can check your insurance’s drug formulary to see if they offer coverage for Rybelsus, Ozempic, Wegovy injections or the Wegovy pill. You’ll be able to compare co-pays and see what the best price is.