Lisinopril is an ACE inhibitor commonly used to treat high blood pressure, heart failure, and to improve your recovery after a heart attack.

ACE inhibitors are medicines that work by relaxing blood vessels and reducing the production of angiotensin II, a hormone that causes blood vessels to tighten. By lowering this effect, lisinopril helps improve blood flow, lower blood pressure, and reduce strain on the heart.

Lisinopril can interact with several medications and supplements, which may affect how it works or increase the risk of side effects. It’s important to tell your healthcare provider about everything you’re taking before starting treatment. Common drug interactions include:

• Potassium supplements
• Diuretics (water pills)
• NSAIDs (such as ibuprofen or naproxen)
• Other blood pressure medications (including other ACE inhibitors, ARBs, or aliskiren)
• Other heart medications (sacubitril/valsartan and similar drugs)
• Antidiabetic medications
• Immunosuppressants (sirolimus)
• Drospirenone-containing birth control pills

Lisinopril is only available with a prescription. This means the use of this drug and all other prescription medications must be authorized by a licensed healthcare provider. If you're looking for a prescription, book a telehealth appointment with Sesame to talk to a provider who can write you a prescription or refill an existing one.

Note that all prescriptions are at the discretion of your healthcare provider. Providers on Sesame cannot prescribe controlled substances.

Several ACE inhibitors are currently available in the U.S., including benazepril, enalapril, enalapril-hydrochlorothiazide (HCTZ), lisinopril-HCTZ, quinapril, and ramipril. These medications are all commonly used to manage high blood pressure, heart failure, and related cardiovascular conditions.

If an ACE inhibitor isn’t right for you, your healthcare provider may recommend alternatives. That may include antihypertensives like [losartan-HCTZ](https://sesamecare.com/medication/losartan-hctz

), which belongs to a class of medications called angiotensin II receptor blockers (ARBs). Your provider can help you find the safest and most effective option based on your individual health needs.