Progesterone pills are primarily used in combination with estrogen for hormone replacement therapy during menopause and perimenopause. Progesterone can help reduce menopausal symptoms and protect the uterus from endometrial overgrowth, which increases cancer risk.
Progesterone comes in other formulations, including vaginal gel, a vaginal insert, and an intramuscular injection. These are typically used for infertility treatment, IVF, abnormal bleeding, and the absence of menstruation.



