Get a Rybelsus (semaglutide) prescription online for type 2 diabetes

While taking Rybelsus (semaglutide), you should avoid eating, drinking (except plain water) or taking other medications for at least 30 minutes after you take it.

You should limit alcohol use and fatty meals (especially if they upset your stomach), as this medication can cause nausea.

Let your doctor know before starting any new medications or supplements to make sure they’re safe to take with Rybelsus.

While taking Rybelsus for weight loss is not an FDA-approved use of the drug, Rybelsus has been shown to cause weight loss in many patients. Research shows that after 6 months, people taking a 7 mg dose of Rybelsus daily lose an average of 5 lbs, while people taking a 14 mg dose of Rybelsus daily lose an average of 8 pounds.

However, if your main goal is weight loss, there are other GLP-1 medications that are FDA-approved for weight management and tend to lead to greater weight loss, including:

• Wegovy pill (oral semaglutide)
• Wegovy (semaglutide)
• Zepbound (tirzepatide)

There are also other GLP-1 medications that are FDA-approved for type 2 diabetes but also include weight loss as a side effect, including:

• Ozempic (semaglutide)
• Mounjaro (tirzepatide)

Your Sesame provider can help determine which medication is best for you, your lifestyle and your budget during your video visit.

The typical starting dose of Rybelsus is 3 mg per day. Your provider will likely keep you on this dose for a month or so while your body adjusts to the medication, then increase your dose to 7 mg or 14 mg daily depending on your blood sugar levels.

Do not stop taking Rybelsus or increase your dose without consulting your provider first. If you begin to experience adverse side effects like nausea, vomiting, decreased appetite or stomach upset while taking this medication, inform your provider right away.

No, Rybelsus and all other forms of semaglutide are available by prescription online. This means the use of this drug must be authorized by a licensed health care provider.

Note that all prescriptions are at the discretion of your health care provider. Providers on Sesame cannot prescribe controlled substances.

No, there are currently no generic alternatives to Rybelsus (semaglutide), although there are other semaglutide medications on the market. These include the Wegovy pill (oral semaglutide), Wegovy (injectable semaglutide), and Ozempic (injectable semaglutide).

If you need assistance with navigating your options, you can schedule a video consult with a provider through Sesame’s Everyday Rx program to discuss the best medication for your needs.

The Everyday Rx program starts at just $29 per month and includes telehealth visits, unlimited messaging, monthly Rx refills and ongoing clinical care from a provider of your choice. The $29 monthly fee does not include the cost of medication.

It's important to note that brand-name GLP-1s like Rybelsus and Ozempic can be expensive without insurance coverage. However, many manufacturers offer reduced cash-pay prices for self-pay patients, as well as weight loss medication savings coupons.

Note that providers on Sesame set their own prices, which means that some providers may offer Everyday Rx at a higher price.

Certain GLP-1 therapies such as semaglutide (the active ingredient in Ozempic, Rybelsus, and Wegovy), liraglutide (the active ingredient in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound) may increase the likelihood of developing thyroid gland tumors, including MTC, a type of thyroid cancer. This conclusion is based on studies where laboratory animals given semaglutide, liraglutide, tirzepatide and other GLP-1 medications developed tumors. However, it is not yet confirmed if these medications pose the same risk to humans. You can find additional information about the risks of FDA-approved medications that contain semaglutide here.

It’s important to inform your doctor if you or any family member has ever had MTC or MEN. If this is the case, your doctor will likely advise against taking GLP-1 medications.

If you are prescribed a GLP-1 medication and exhibit any of the following symptoms, you should contact your provider immediately:

• A lump or swelling in the neck
  
• Hoarseness
  
• Difficulty swallowing
  
• Shortness of breath
  
• Severe abdominal pain

Before taking GLP-1 medications, you should also discuss the following with your provider:

Allergies: Inform your doctor and pharmacist of any allergies you have to semaglutide (including under brand names Ozempic, Rybelsus, Wegovy) or similar medications such as tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon BCise, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy) and lixisenatide (Adlyxin, or in Soliqua).

Personal and family medical history: Be sure to disclose if you have a history of medical conditions like pancreatitis, diabetic retinopathy, gallbladder disease, kidney disease, or thyroid cancer. Inform your doctor about recent episodes of diarrhea, nausea, vomiting or any inability to consume liquids, which could lead to dehydration.

Current medications and supplements: Provide a comprehensive list of all medicines and supplements you are currently taking, including prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products. This is crucial as GLP-1 medications can alter how your body absorbs oral medications.

Pregnancy and breastfeeding: Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon.

Surgical procedures: In the event of surgery, including dental procedures, inform the medical or dental professional that you are on GLP-1 medication.

It's essential to thoroughly discuss these risks with your healthcare provider and consider your personal and family medical history when deciding whether to use these medications. Your doctor can provide guidance on the best course of action based on your specific health situation.