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Get a Zepbound (tirzepatide) prescription online for weight management and sleep apnea

  • Same-day prescriptions
  • Local pharmacy pick-up
  • Hassle-free Rx refills

Book care online through Sesame's weight loss program to see if a Zepbound (tirzepatide) prescription or another GLP-1 medication is right for you. Zepbound is a once-weekly injection that is FDA-approved for chronic weight management when used with diet and exercise. It’s also approved to treat moderate to severe obstructive sleep apnea (OSA) in adults with obesity.

This medication can help you:

  • Reduce body weight
  • Support better sleep
  • Improve metabolic health

Zepbound is sometimes used off-label to support people with heart failure with preserved ejection fraction (HFpEF) or improve liver health in those with metabolic dysfunction-associated steatohepatitis (MASH).

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Why should you get Zepbound online through Sesame?

Zepbound overview

Learn more about Zepbound, what it's used to treat, and how you can get a Zepbound prescription today.

Last medically reviewed by: Allison Edwards, MD, Medical Director
All content on this page has been reviewed for medical accuracy to reflect the latest standards of care and clinical evidence.

Start your affordable Zepbound journey with Success by Sesame for just $59/mo.

How to get a prescription for Zepbound through Sesame

1
Tell us about your weight loss history & goals

Answer a few questions to help us personalize your weight loss program, then choose your Sesame provider.

2
Meet with your Sesame provider

Talk to your provider about your medical history and weight loss goals in a video consult. They’ll tailor a treatment plan and order a lab test if metabolic data is needed.

3
Begin treatment

Your provider will prescribe a weight loss medication like Zepbound if it’s right for you. Sesame will send the medication to your door or preferred pharmacy.

4
Receive ongoing support

Enjoy unlimited provider messaging, follow-up visits, and app features that make it easy to track weight loss, lifestyle goals & side effects.

Zepbound side effects & dosages

Learn about potential side effects and when to seek medical care.

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Zepbound is a prescription medication used to help patients manage their weight. It is also FDA-approved to treat obstructive sleep apnea (OSA) in adults with obesity.

It is currently indicated for use in adults with obesity (with a BMI of 30 kg/m2 or greater) or overweight adults (with a BMI of 27 kg/m2 or greater) who also have weight-related medical problems such as type 2 diabetes, high blood pressure, obstructive sleep apnea, or cardiovascular disease.

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist drug.

Dual GIP and GLP-1 drugs target multiple pathways that influence appetite regulation and metabolism. Firstly, they stimulate insulin release from the pancreas in response to elevated blood sugar levels, aiding in glucose control. They also inhibit the release of glucagon, which further contributes to blood sugar regulation.

However, the unique feature of dual GIP and GLP-1 drugs is their impact on appetite. They significantly slow down stomach emptying, leading to a prolonged sense of fullness after meals, reducing food intake, and preventing overeating.

Healthcare providers prescribe Zepbound in conjunction with a reduced-calorie diet and increased physical activity.

Zepbound is prescribed as a single-dose pen, a multi-dose KwikPen, or as a single-dose vial. The dosing of Zepbound for weight management may vary depending on your individual needs and your healthcare provider's guidance.

Your healthcare provider will determine the initial dose and any dose adjustments based on your body’s response and the goal of achieving optimal weight management. Do not discontinue or change your Zepbound dosage without consulting your healthcare provider.

No, Zepbound is available by prescription only. A licensed healthcare provider must authorize its use.

Looking for a prescription? A Success by Sesame provider can assess your eligibility and prescribe Zepbound if it's appropriate for your medical condition and needs. Depending on the medication, you can arrange for same-day pickup at your pharmacy. Book an online consultation with a licensed provider on Sesame today to determine whether Zepbound might be right for you.

Note that all prescriptions are at the discretion of your healthcare provider. Sesame cannot guarantee that you will be provided a prescription after a video or in-person appointment.

The Success by Sesame subscription starts at just $99 per month and includes telehealth visits, unlimited messaging, and ongoing clinical care from a provider of your choice. The $99 subscription fee does not include the cost of medication.

It's important to note that brand-name GLP-1 receptor agonist medications can be expensive without insurance coverage. However, many manufacturers offer reduced cash-pay prices for self-pay patients, as well as weight loss medication savings coupons.

If you are insured, your provider can assist with insurance pre-authorization paperwork to help reduce the cost of your medication.

Note that providers on Sesame set their own prices, which means that some providers may offer the service at a higher price.

Certain GLP-1 therapies such as semaglutide (the active ingredient in Ozempic, Rybelsus, and Wegovy), liraglutide (the active ingredient in Saxenda and Victoza), and tirzepatide (the active ingredient in Mounjaro and Zepbound) may increase the likelihood of developing thyroid gland tumors, including MTC, a type of thyroid cancer. This conclusion is based on studies where laboratory animals given semaglutide, liraglutide, tirzepatide and other GLP-1 medications developed tumors. However, it is not yet confirmed if these medications pose the same risk to humans. You can find additional information about the risks of FDA-approved medications that contain semaglutide here.

It’s important to inform your doctor if you or any family member has ever had MTC or MEN. If this is the case, your doctor will likely advise against taking GLP-1 medications.

If you are prescribed a GLP-1 medication and exhibit any of the following symptoms, you should contact your provider immediately:

  • A lump or swelling in the neck
  • Hoarseness
  • Difficulty swallowing
  • Shortness of breath
  • Severe abdominal pain

Before taking GLP-1 medications, you should also discuss the following with your provider:

Allergies: Inform your doctor and pharmacist of any allergies you have to semaglutide (including under brand names Ozempic, Rybelsus, Wegovy) or similar medications such as tirzepatide (Mounjaro, Zepbound), dulaglutide (Trulicity), exenatide (Bydureon BCise, Byetta), liraglutide (Saxenda, Victoza, or in Xultophy) and lixisenatide (Adlyxin, or in Soliqua).

Personal and family medical history: Be sure to disclose if you have a history of medical conditions like pancreatitis, diabetic retinopathy, gallbladder disease, kidney disease, or thyroid cancer. Inform your doctor about recent episodes of diarrhea, nausea, vomiting or any inability to consume liquids, which could lead to dehydration.

Current medications and supplements: Provide a comprehensive list of all medicines and supplements you are currently taking, including prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products. This is crucial as GLP-1 medications can alter how your body absorbs oral medications.

Pregnancy and breastfeeding: Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon.

Surgical procedures: In the event of surgery, including dental procedures, inform the medical or dental professional that you are on GLP-1 medication.

It's essential to thoroughly discuss these risks with your healthcare provider and consider your personal and family medical history when deciding whether to use these medications. Your doctor can provide guidance on the best course of action based on your specific health situation.