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Same-day online depression treatment & antidepressant prescriptions

Get fast, affordable help for depression as soon as today. Book now with a licensed mental health provider who will review your depression symptoms, mental health history and medications to create a personalized treatment plan. Your treatment plan may include prescriptions for medication or therapy sessions — no insurance needed.

Available to all patients (those under 18 must have an adult present).

About depression

How to get depression treatment and antidepressant prescription online with Sesame

1
Choose a provider

Browse mental health provider reviews, same-day time slots, and upfront prices as low as $34 before you book.

2
Meet with your provider

Discuss your depression symptoms and mental health history during a face-to-face video call with your online doctor or clinician.

3
Get depression medication prescribed online

If your Sesame provider prescribes antidepressants as part of your treatment plan, your Rx will be sent to your preferred pharmacy for same-day pickup.

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Patients who trust Sesame’s online depression treatment & antidepressant prescription services

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About Depression

Depression, also known as major depressive disorder or clinical depression, is a type of mood disorder that negatively affects how you think, behave, and feel. Untreated depression can lead to a range of emotional and physical issues.

According to Psychiatry.org, depression affects nearly one in fifteen adults, with one in six people experiencing depression at least once in their lifetime.

Depression symptoms

Depressive disorders will cause different symptoms in different people. These thoughts and sensations will vary from person to person.
Common symptoms of depression include:

  • Feelings of sadness
  • Loss of interest in or pleasure in most normal activities
  • Outbursts of anger or frustration
  • Troubles with sleep such as sleeping too much or insomnia
  • Fatigue or lack of energy
  • Anxiety or agitation
  • Loss of appetite or increased craving for food
  • Feelings of worthlessness
  • Suicidal thoughts

If you are experiencing symptoms of depression, talk to a doctor or mental health care provider right away.

If you think you might hurt yourself or are experiencing suicidal thoughts, call your doctor or a suicide hotline to speak to a mental health professional. In the U.S., the National Suicide Prevention Lifeline 1-800-273-TALK (1-800-273-8255) or text 741741.

Types of depression


Depression can make it difficult to carry out day-to-day tasks and affect personal relationships.

There are many types of depression caused by a variety of triggers, sometimes chemical and sometimes the result of traumatic life events. These include:

Major depression: People with major depression have depressed moods most of the day for most days of the week.

Persistent Depressive Disorder: If a person has depression for 2 or more years, this is known as persistent depressive disorder. This type of depression has two subgroups called chronic major depression and dysthymia, or low-grade persistent depression.

Bipolar Disorder: Also known as manic depression, a person with bipolar disorder has extremes, ranging from states of low energy and/or mood to periods of high energy and/or mood. Also known as manic depression, bipolar disorder can be treated with mood stabilizer medication, such as Latuda, Seroquel, and Olanzapine-fluoxetine combo.

Seasonal Affective Disorder (SAD): A person who has seasonal affective disorder will often feel periods of major depression during winter. Because winter days are shorter than the rest of the year, a person receives less and less sunlight which can cause seasonal affective disorder. Antidepressants may be a great option for someone who has SAD.

Psychotic Depression: If a person has paranoia, hallucinations, and/or delusions during periods of major depression, they may be suffering from psychotic depression. This type of depression can be treated with antipsychotic drugs along with antidepressants.

Peripartum (Postpartum) Disorder: Postpartum depression affects new mothers, typically in the weeks and months post-childbirth.

Premenstrual Dysphoric Disorder (PMDD): This type of depression affects people at the onset of their monthly period. Along with depression, you may feel tired, irritable, unfocused, anxious, overwhelmed, or have changes in your sleep patterns. PMDD can be treated with some birth controls and antidepressants.

‘Situational’ Depression (Stress response syndrome): This is caused by a traumatic or stressful event like moving, divorce, losing your job, or a death in the family, and can likely be treated with psychotherapy.

Atypical Depression: Unlike typical depression, this depression follows more unusual patterns such as feeling overly sensitive to critique, finding you have increased your appetite, sleeping more than usual, or your arms and/or legs feeling heavy.

Complications of depression


Depression is more than just feeling sad. These feelings are persistent and require treatment. If left untreated, depression can lead to complications such as:

  • Social isolation
  • Anxiety disorders
  • Weight gain/ weight loss
  • Eating disorders (like anorexia or bulimia)
  • Self-mutilation
  • Suicidal thoughts or behaviors
  • Alcohol or drug abuse

If you or someone you know is dealing with symptoms of a depressive disorder, seek help from a licensed mental health care provider right away.

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Pay per visit or subscribe to Mental Health Rx for $79/month and get all of the following:
  • Same-day Rx refills for multiple medications
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Frequently asked questions

About online depression medication

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Medically reviewed by:Dr. Allison Edwards, MD

Yes, many types of depression can be treated online with the help of evaluation and care from a licensed mental health provider.

Sesame offers convenient and affordable online mental health visits with licensed health providers across the country.

If your provider determines that you are experiencing some form of depressive disorder, they will discuss a treatment plan with you. This may include recurring video psychiatry consults, therapy sessions and or medication. They may also suggest lifestyle changes related to nutrition and exercise to improve your mental health.

Antidepressants are medicines that help balance certain brain chemicals that affect mood, energy, and motivation. When those chemicals are out of sync, you might feel persistently sad, anxious, irritable, or even emotionless.

These medications don’t create “happiness,” but they can make it easier for your brain to return to a steadier, more stable state. Over time, this can help improve your mental health, sleep, focus, appetite, and your ability to enjoy things again.

Some of the most common antidepressants for depression and anxiety include SSRIs like Zoloft (sertraline), Lexapro (escitalopram), and Prozac (fluoxetine), as well as SNRIs like Cymbalta (duloxetine) and Effexor (venlafaxine).

Depression medications usually take a few weeks to begin to work, and they’re often most helpful when combined with in-person or online therapy sessions and healthy habits.

No, antidepressants are not available over the counter. They require a prescription from a licensed healthcare provider, such as a doctor or nurse practitioner.

This is because antidepressants affect brain chemistry and need to be chosen carefully based on your specific depression symptoms, medical history, and any other medications you may be taking.

Depression medication requires a prescription from a licensed healthcare provider, so you can’t directly buy it online. However, you can get an online prescription through telehealth platforms like Sesame, where you’ll be able to book a virtual doctor’s appointment with a provider who can write a prescription for depression medication if it’s clinically appropriate.

After your visit, your Sesame provider can send any prescribed medications to your local pharmacy for pickup or arrange for mail delivery, depending on your preference.

Yes! Sesame makes it affordable and convenient to get a new depression medication prescription or refill a prescription from the comfort of your own home!

To discuss a new online prescription or refill, book a mental health appointment with a doctor or nurse on Sesame. If antidepressants or another type of medication is prescribed for your depression symptoms, you’ll be able to pick up your Rx at your preferred pharmacy or get it delivered right to your door.

Note that providers on Sesame cannot prescribe controlled substances.

During your online mental health appointment, you’ll have a private telehealth session with a licensed primary care provider or mental health provider on Sesame who can help start a conversation with you about your mental health symptoms, medical history, lifestyle and other health information.

Depending on your needs, your provider may explore concerns related to:

  • Trauma or PTSD
  • Depression or anxiety
  • Personality disorders
  • Obsessive-compulsive disorder (OCD)
  • Schizophrenia
  • Bipolar disorder
  • Eating disorders
  • Phobias
  • Sexual health or dysfunction
  • Relationship challenges
  • Sleep issues

At the end of your consultation, your Sesame mental health professional may prescribe medication or other treatments, such as cognitive behavioral therapy, to help you feel your best. They may also offer recommendations for follow-up care or additional services.

Yes! Telehealth platforms like Sesame now make it easier than ever to see mental health care professionals for psychiatry consults and therapy sessions. Mental health professionals on Sesame offer a wide range of psychiatry services such as:

  • Talk therapy sessions
  • Cognitive behavioral therapy (CBT)
  • Psychiatric evaluations
  • Behavioral health consultations
  • Couples therapy sessions
  • Medication management (prescriptions and refills)

In addition, licensed mental health professionals on Sesame can address and treat mental health conditions such as:

Depression

This is not a complete list of psychiatric services offered by mental health professionals on Sesame. Use our search bar to look for the specific type of psychiatric care or treatment and book an appointment at your convenience.

To prepare for your video mental health appointment on Sesame, it is recommended that you have a stable internet connection and a private space to conduct the appointment. For your privacy, a quiet and secluded space in your home is the best place to have this video consultation.

It is generally recommended for all psychiatry consultations to jot down a few questions or concerns you may have prior to your appointment. Mental health professionals on Sesame do have the extensive experience needed to help walk you through the consultation, but it is still encouraged to come up with some questions or thoughts of your own to get the most out of your appointment.

If any other preparation is needed, your provider will reach out to discuss these specifics with you.

Most video mental health appointments will start with an initial consultation about your mental health history, symptoms you may be experiencing, medication you are currently taking, and your history with psychiatric care.

After this, your mental health provider can recommend the best treatment plan for you. This may include in-person or online therapy sessions (including cognitive behavioral therapy), a referral to a specialist, or medication management.